IL123322A0 - Tetrahydroquinolines their preparation and pharmaceutical compositions containing them - Google Patents

Tetrahydroquinolines their preparation and pharmaceutical compositions containing them

Info

Publication number: IL123322A0
Authority: IL; Israel
Prior art keywords: tetrahydroquinolines; preparation; pharmaceutical compositions; compositions containing; pharmaceutical
Prior art date: 1995-09-29

Application number

IL12332296A

Other languages

English (en)

Original Assignee

Glaxo Wellcome Spa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-09-29

Filing date

1996-09-26

Publication date

1998-09-24

1995-09-29 Priority claimed from GBGB9519893.3A external-priority patent/GB9519893D0/en

1996-08-17 Priority claimed from GBGB9617306.7A external-priority patent/GB9617306D0/en

1996-09-26 Application filed by Glaxo Wellcome Spa filed Critical Glaxo Wellcome Spa

1998-09-24 Publication of IL123322A0 publication Critical patent/IL123322A0/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Psychiatry (AREA)
Hospice & Palliative Care (AREA)
Virology (AREA)
Molecular Biology (AREA)
Pain & Pain Management (AREA)
Cardiology (AREA)
AIDS & HIV (AREA)
Tropical Medicine & Parasitology (AREA)
Addiction (AREA)
Communicable Diseases (AREA)
Heart & Thoracic Surgery (AREA)
Oncology (AREA)
Otolaryngology (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)

IL12332296A 1995-09-29 1996-09-26 Tetrahydroquinolines their preparation and pharmaceutical compositions containing them IL123322A0 (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
GBGB9519893.3A GB9519893D0 (en)	1995-09-29	1995-09-29	Heterocyclic compounds
GBGB9617306.7A GB9617306D0 (en)	1996-08-17	1996-08-17	Heterocyclic compounds
PCT/EP1996/004206 WO1997012870A1 (en)	1995-09-29	1996-09-26	Tetrahydroquinolines as nmda antagonists

Publications (1)

Publication Number	Publication Date
IL123322A0 true IL123322A0 (en)	1998-09-24

Family

ID=26307841

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL12332296A IL123322A0 (en)	1995-09-29	1996-09-26	Tetrahydroquinolines their preparation and pharmaceutical compositions containing them

Country Status (28)

Country	Link
US (1)	US5977136A (xx)
EP (1)	EP0854867B1 (xx)
JP (1)	JP4108123B2 (xx)
KR (1)	KR100464895B1 (xx)
CN (1)	CN1130346C (xx)
AP (1)	AP876A (xx)
AR (1)	AR005233A1 (xx)
AT (1)	ATE221520T1 (xx)
AU (1)	AU708148B2 (xx)
BR (1)	BR9610733A (xx)
CA (1)	CA2232509A1 (xx)
CZ (1)	CZ292379B6 (xx)
DE (1)	DE69622731T2 (xx)
DK (1)	DK0854867T3 (xx)
EA (1)	EA000875B1 (xx)
ES (1)	ES2180799T3 (xx)
HU (1)	HUP9900040A3 (xx)
IL (1)	IL123322A0 (xx)
IS (1)	IS4677A (xx)
MX (1)	MX9801967A (xx)
NO (1)	NO310355B1 (xx)
NZ (1)	NZ319596A (xx)
PL (1)	PL186781B1 (xx)
PT (1)	PT854867E (xx)
SI (1)	SI0854867T1 (xx)
TR (1)	TR199800531T1 (xx)
TW (1)	TW460465B (xx)
WO (1)	WO1997012870A1 (xx)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9617305D0 (en)	1996-08-17	1996-09-25	Glaxo Wellcome Spa	Heterocyclic compounds
GB9706294D0 (en) *	1997-03-26	1997-05-14	Glaxo Wellcome Spa	Heterocyclic compound
MY125037A (en) *	1998-06-10	2006-07-31	Glaxo Wellcome Spa	1,2,3,4 tetrahydroquinoline derivatives
TW555757B (en) *	1998-07-31	2003-10-01	Akzo Nobel Nv	Aminomethylcarboxylic acid derivatives
AU5194999A (en) *	1998-08-07	2000-02-28	Takeda Chemical Industries Ltd.	Benzothiepin derivatives, process for the preparation of the same and uses thereof
GB9929037D0 (en) *	1999-12-08	2000-02-02	Glaxo Wellcome Spa	Heterocyclic derivatives
NZ533566A (en) *	2001-12-28	2007-03-30	Acadia Pharm Inc	Tetrahydroquinoline analogues as muscarinic agonists
DE10236910A1 (de) *	2002-08-12	2004-03-11	Grünenthal GmbH	Substituierte 1,2,3,4-Tetrahydrochinolinderivate
RU2451014C2 (ru) *	2005-07-22	2012-05-20	Мотида Фармасьютикал Ко., Лтд.	Новое производное гетероциклиден ацетамида
NZ565080A (en)	2005-07-22	2011-03-31	Mochida Pharm Co Ltd	Novel heterocyclidene acetamide derivative
RU2010140442A (ru)	2008-03-05	2012-04-10	Бёрингер Ингельхайм Интернациональ Гмбх (De)	Трициклические производные пиридина, лекарственные средства, содержащие такие соединения, их применение и способ их получения
EP2286808A1 (en) *	2009-08-18	2011-02-23	Rheinische Friedrich-Wilhelms Universität	Cytohesin inhibitors
WO2011101774A1 (en)	2010-02-16	2011-08-25	Pfizer Inc.	(r)-4-((4-((4-(tetrahydrofuran-3-yloxy)benzo[d]isoxazol-3-yloxy)methyl)piperidin-1-yl)methyl)tetrahydro-2h-pyran-4-ol, a partial agonist of 5-ht4 receptors
MA34007B1 (fr)	2010-02-19	2013-02-01	Boehringer Ingelheim Int	Derives de pyridine tricycliques medicaments contenant ces composes leur utilisation et leur procede de preparation
JP5947382B2 (ja)	2011-08-17	2016-07-06	ベーリンガーインゲルハイムインターナショナルゲゼルシャフトミットベシュレンクテルハフツング	フロ［３，４−ｃ］キノリン誘導体、このような化合物を含む薬物、それらの使用及びそれらの調製方法
WO2016114655A1 (en) *	2015-01-12	2016-07-21	Ry Pharma B.V.	Treating neuromuscular or neurologic disease through reducing gabaergic and/or glycinergic inhibitory neurotransmitter overstimulation
WO2017065602A1 (en) *	2015-10-13	2017-04-20	Ry Pharma B.V.	Treating neuromuscular or neurologic disease through reducing gabaergic and/or glycinergic inhibitory neurotransmitter overstimulation

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IL93610A0 (en) *	1989-03-08	1990-12-23	Merck Sharp & Dohme	Tetrahydroquinoline derivatives,their preparation and pharmaceutical compositions containing them

1996
- 1996-09-26 AP APAP/P/1998/001212A patent/AP876A/en active
- 1996-09-26 PT PT96933399T patent/PT854867E/pt unknown
- 1996-09-26 CA CA002232509A patent/CA2232509A1/en not_active Abandoned
- 1996-09-26 CZ CZ1998940A patent/CZ292379B6/cs not_active IP Right Cessation
- 1996-09-26 EA EA199800230A patent/EA000875B1/ru not_active IP Right Cessation
- 1996-09-26 KR KR10-1998-0702321A patent/KR100464895B1/ko not_active Expired - Fee Related
- 1996-09-26 TR TR1998/00531T patent/TR199800531T1/xx unknown
- 1996-09-26 EP EP96933399A patent/EP0854867B1/en not_active Expired - Lifetime
- 1996-09-26 NZ NZ319596A patent/NZ319596A/en not_active IP Right Cessation
- 1996-09-26 BR BR9610733A patent/BR9610733A/pt not_active IP Right Cessation
- 1996-09-26 AU AU72148/96A patent/AU708148B2/en not_active Ceased
- 1996-09-26 CN CN96198560A patent/CN1130346C/zh not_active Expired - Fee Related
- 1996-09-26 DE DE69622731T patent/DE69622731T2/de not_active Expired - Lifetime
- 1996-09-26 PL PL96325966A patent/PL186781B1/pl not_active IP Right Cessation
- 1996-09-26 AT AT96933399T patent/ATE221520T1/de not_active IP Right Cessation
- 1996-09-26 ES ES96933399T patent/ES2180799T3/es not_active Expired - Lifetime
- 1996-09-26 WO PCT/EP1996/004206 patent/WO1997012870A1/en active IP Right Grant
- 1996-09-26 IL IL12332296A patent/IL123322A0/xx not_active IP Right Cessation
- 1996-09-26 JP JP51394797A patent/JP4108123B2/ja not_active Expired - Fee Related
- 1996-09-26 SI SI9630523T patent/SI0854867T1/xx unknown
- 1996-09-26 US US09/029,860 patent/US5977136A/en not_active Expired - Fee Related
- 1996-09-26 HU HU9900040A patent/HUP9900040A3/hu unknown
- 1996-09-26 DK DK96933399T patent/DK0854867T3/da active
- 1996-09-30 AR ARP960104543A patent/AR005233A1/es active IP Right Grant
- 1996-10-04 TW TW085112168A patent/TW460465B/zh not_active IP Right Cessation
1998
- 1998-02-27 IS IS4677A patent/IS4677A/is unknown
- 1998-03-12 MX MX9801967A patent/MX9801967A/es not_active IP Right Cessation
- 1998-03-27 NO NO19981396A patent/NO310355B1/no not_active IP Right Cessation

Also Published As

Publication number	Publication date
CN1130346C (zh)	2003-12-10
NO981396L (no)	1998-05-27
AU7214896A (en)	1997-04-28
JPH11512728A (ja)	1999-11-02
PL186781B1 (pl)	2004-02-27
SI0854867T1 (en)	2003-02-28
KR19990063850A (ko)	1999-07-26
PL325966A1 (en)	1998-08-17
JP4108123B2 (ja)	2008-06-25
ATE221520T1 (de)	2002-08-15
EP0854867B1 (en)	2002-07-31
ES2180799T3 (es)	2003-02-16
PT854867E (pt)	2002-12-31
MX9801967A (es)	1998-08-30
HUP9900040A3 (en)	2001-01-29
NZ319596A (en)	1999-09-29
KR100464895B1 (ko)	2005-05-16
TW460465B (en)	2001-10-21
AP9801212A0 (en)	1998-03-31
AP876A (en)	2000-09-27
NO981396D0 (no)	1998-03-27
AU708148B2 (en)	1999-07-29
DK0854867T3 (da)	2002-12-02
EP0854867A1 (en)	1998-07-29
DE69622731D1 (de)	2002-09-05
EA199800230A1 (ru)	1998-10-29
US5977136A (en)	1999-11-02
DE69622731T2 (de)	2003-02-20
CZ94098A3 (cs)	1998-07-15
TR199800531T1 (xx)	1998-06-22
EA000875B1 (ru)	2000-06-26
WO1997012870A1 (en)	1997-04-10
BR9610733A (pt)	1999-07-13
CZ292379B6 (cs)	2003-09-17
AR005233A1 (es)	1999-04-28
CA2232509A1 (en)	1997-04-10
HUP9900040A2 (hu)	1999-04-28
CN1202887A (zh)	1998-12-23
HK1009133A1 (en)	1999-05-28
NO310355B1 (no)	2001-06-25
IS4677A (is)	1998-02-27

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Legal Events

Date	Code	Title
2001-06-14	KB	Patent renewed
2002-11-10	KB	Patent renewed
2006-10-30	KB	Patent renewed
2011-06-30	MM9K	Patent not in force due to non-payment of renewal fees