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JPH07503477A - バッカチン３および１０‐デアセチルバッカチン３の新規誘導体，それらの製造およびそれらを含有する医薬組成物 - Google Patents

バッカチン３および１０‐デアセチルバッカチン３の新規誘導体，それらの製造およびそれらを含有する医薬組成物

Info

Publication number
JPH07503477A
JPH07503477A JP5513823A JP51382393A JPH07503477A JP H07503477 A JPH07503477 A JP H07503477A JP 5513823 A JP5513823 A JP 5513823A JP 51382393 A JP51382393 A JP 51382393A JP H07503477 A JPH07503477 A JP H07503477A
Authority
JP
Japan
Prior art keywords
group
carbon atoms
groups
general formula
once
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP5513823A
Other languages
English (en)
Japanese (ja)
Inventor
ブルザ，ジヤン−ドミニク
コメルソン，アラン
Original Assignee
ローン−プーラン・ロレ・ソシエテ・アノニム
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ローン−プーラン・ロレ・ソシエテ・アノニム filed Critical ローン−プーラン・ロレ・ソシエテ・アノニム
Publication of JPH07503477A publication Critical patent/JPH07503477A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
JP5513823A 1992-02-07 1993-02-04 バッカチン３および１０‐デアセチルバッカチン３の新規誘導体，それらの製造およびそれらを含有する医薬組成物 Pending JPH07503477A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR9201381A FR2687151B1 (fr) 1992-02-07 1992-02-07 Nouveaux derives de la baccatine iii et de la desacetyl-10 baccatine iii, leur preparation et les compositions pharmaceutiques qui les contiennent.
FR92/01381 1992-02-07
PCT/FR1993/000112 WO1993016060A1 (fr) 1992-02-07 1993-02-04 Nouveaux derives de la baccatine iii et de la desacetyl-10 baccatine iii, leur preparation et les compositions pharmaceutiques qui les contiennent

Publications (1)

Publication Number Publication Date
JPH07503477A true JPH07503477A (ja) 1995-04-13

Family

ID=9426426

Family Applications (1)

Application Number Title Priority Date Filing Date
JP5513823A Pending JPH07503477A (ja) 1992-02-07 1993-02-04 バッカチン３および１０‐デアセチルバッカチン３の新規誘導体，それらの製造およびそれらを含有する医薬組成物

Country Status (14)

Country Link
EP (1) EP0625148A1 (fr)
JP (1) JPH07503477A (fr)
AU (1) AU3505093A (fr)
CA (1) CA2127372A1 (fr)
CZ (1) CZ187294A3 (fr)
FI (1) FI943645L (fr)
FR (1) FR2687151B1 (fr)
HU (1) HU9402292D0 (fr)
MX (1) MX9300628A (fr)
NO (1) NO942910L (fr)
SK (1) SK92794A3 (fr)
TW (1) TW242139B (fr)
WO (1) WO1993016060A1 (fr)
ZA (1) ZA93821B (fr)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998002426A1 (fr) * 1996-07-15 1998-01-22 Kabushiki Kaisha Yakult Honsha Derives de taxane et medicaments les contenant
WO1999014209A1 (fr) * 1997-09-17 1999-03-25 Kabushiki Kaisha Yakult Honsha Nouveaux derives de taxane
US6509484B2 (en) 1993-02-05 2003-01-21 Napro Biotherapeutics, Inc. Synthesis of taxol, taxol analogs and their intermediates with variable a-ring side chain structures and compositions thereof
JP2011517455A (ja) * 2008-03-31 2011-06-09 フロリダ・ステイト・ユニバーシティ・リサーチ・ファウンデイション・インコーポレイテッド Ｃ（１０）エチルエステルおよびｃ（１０）シクロプロピルエステル置換タキサン

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5698582A (en) * 1991-07-08 1997-12-16 Rhone-Poulenc Rorer S.A. Compositions containing taxane derivatives
US6794523B2 (en) 1991-09-23 2004-09-21 Florida State University Taxanes having t-butoxycarbonyl substituted side-chains and pharmaceutical compositions containing them
FR2696459B1 (fr) * 1992-10-05 1994-11-25 Rhone Poulenc Rorer Sa Procédé de préparation de dérivés du taxane.
MX9307777A (es) 1992-12-15 1994-07-29 Upjohn Co 7-HALO-Y 7ß, 8ß-METANO-TAXOLES, USO ANTINEOPLASTICO Y COMPOSICIONES FARMACEUTICAS QUE LOS CONTIENEN.
US5684175A (en) * 1993-02-05 1997-11-04 Napro Biotherapeutics, Inc. C-2' hydroxyl-benzyl protected, N-carbamate protected (2R, 3S)- 3-phenylisoserine and production process therefor
EP0982302B1 (fr) * 1993-06-11 2004-04-14 PHARMACIA & UPJOHN COMPANY Delta 6,7-taxols usage antineoplastique et compositions pharmaceutiques les contenant
IL112412A (en) * 1994-01-28 2000-02-29 Upjohn Co Delta 12,13-iso-taxol analogs and antineoplastic pharmaceutical compositions containing them
GB9512471D0 (en) * 1995-06-20 1995-08-23 Pharmacia Spa Method for the preparation of taxol and its derivatives
US6107497A (en) * 1996-02-29 2000-08-22 Napro Biotherapeutics, Inc. Intermediate for use in docetaxel synthesis and production method therefor
US5750737A (en) * 1996-09-25 1998-05-12 Sisti; Nicholas J. Method for paclitaxel synthesis
WO2002066448A1 (fr) * 2001-02-20 2002-08-29 Dabur India Limited Procede de preparation de paclitaxel (taxol) utilisant un acide 3-(alk-2-ynyloxy) carbonyl-5-oxazolidine carboxylique
AU2008288651A1 (en) * 2007-08-22 2009-02-26 6570763 Canada Inc. Process for converting 9-dihydro-13-acetylbaccatin III into docetaxel or paclitaxel

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6509484B2 (en) 1993-02-05 2003-01-21 Napro Biotherapeutics, Inc. Synthesis of taxol, taxol analogs and their intermediates with variable a-ring side chain structures and compositions thereof
WO1998002426A1 (fr) * 1996-07-15 1998-01-22 Kabushiki Kaisha Yakult Honsha Derives de taxane et medicaments les contenant
CN1097044C (zh) * 1996-07-15 2002-12-25 亚库尔特株式会社总社 紫杉烷衍生物以及含有该衍生物的药物
WO1999014209A1 (fr) * 1997-09-17 1999-03-25 Kabushiki Kaisha Yakult Honsha Nouveaux derives de taxane
US6136808A (en) * 1997-09-17 2000-10-24 Kabushiki Kaisha Yakult Honsha Taxane derivatives
JP2011517455A (ja) * 2008-03-31 2011-06-09 フロリダ・ステイト・ユニバーシティ・リサーチ・ファウンデイション・インコーポレイテッド Ｃ（１０）エチルエステルおよびｃ（１０）シクロプロピルエステル置換タキサン

Also Published As

Publication number Publication date
FI943645A7 (fi) 1994-08-05
FR2687151A1 (fr) 1993-08-13
FI943645A0 (fi) 1994-08-05
HU9402292D0 (en) 1994-11-28
NO942910L (no) 1994-08-05
TW242139B (fr) 1995-03-01
CZ187294A3 (en) 1995-01-18
WO1993016060A1 (fr) 1993-08-19
FR2687151B1 (fr) 1994-03-25
AU3505093A (en) 1993-09-03
SK92794A3 (en) 1995-04-12
CA2127372A1 (fr) 1993-08-19
FI943645L (fi) 1994-08-05
NO942910D0 (fr) 1994-08-05
MX9300628A (es) 1993-08-01
EP0625148A1 (fr) 1994-11-23
ZA93821B (en) 1993-09-09

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