PT1159279E - 4-oxo-4,7-di-hidrotieno¬2,3-b|piridino-5-carboxamidas como agentes antivirais - Google Patents

4-oxo-4,7-di-hidrotieno¬2,3-b|piridino-5-carboxamidas como agentes antivirais

Info

Publication number: PT1159279E
Authority: PT; Portugal
Prior art keywords: dihydrotiene; carboxamides; oxo; pyridine; antiviral agents
Prior art date: 1999-03-09

Application number

PT00913786T

Other languages

English (en)

Inventor

Mark E Schnute

Michele M Cudahy

Allen Scott

Original Assignee

Upjohn Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-03-09

Filing date

2000-03-07

Publication date

2003-02-28

2000-03-07 Application filed by Upjohn Co filed Critical Upjohn Co

2003-02-28 Publication of PT1159279E publication Critical patent/PT1159279E/pt

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Virology (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Engineering & Computer Science (AREA)
Biotechnology (AREA)
Molecular Biology (AREA)
Bioinformatics & Cheminformatics (AREA)
Immunology (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Hydrogenated Pyridines (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Heterocyclic Compounds Containing Sulfur Atoms (AREA)

PT00913786T 1999-03-09 2000-03-07 4-oxo-4,7-di-hidrotieno¬2,3-b|piridino-5-carboxamidas como agentes antivirais PT1159279E (pt)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US12366099P	1999-03-09	1999-03-09

Publications (1)

Publication Number	Publication Date
PT1159279E true PT1159279E (pt)	2003-02-28

Family

ID=22410054

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PT00913786T PT1159279E (pt)	1999-03-09	2000-03-07	4-oxo-4,7-di-hidrotieno¬2,3-b\|piridino-5-carboxamidas como agentes antivirais

Country Status (25)

Country	Link
US (2)	US6239142B1 (pt)
EP (1)	EP1159279B1 (pt)
JP (1)	JP2002539130A (pt)
KR (1)	KR20010102543A (pt)
CN (1)	CN1347417A (pt)
AT (1)	ATE226208T1 (pt)
AU (1)	AU759875B2 (pt)
BR (1)	BR0008804A (pt)
CA (1)	CA2366609A1 (pt)
CZ (1)	CZ20013028A3 (pt)
DE (1)	DE60000611T2 (pt)
DK (1)	DK1159279T3 (pt)
EA (1)	EA003607B1 (pt)
ES (1)	ES2184705T3 (pt)
HK (1)	HK1045518A1 (pt)
HU (1)	HUP0200324A3 (pt)
IL (1)	IL145005A0 (pt)
NO (1)	NO20014363L (pt)
NZ (1)	NZ513758A (pt)
PL (1)	PL350651A1 (pt)
PT (1)	PT1159279E (pt)
SK (1)	SK12582001A3 (pt)
TW (1)	TWI222451B (pt)
WO (1)	WO2000053610A2 (pt)
ZA (1)	ZA200107255B (pt)

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US6562822B2 (en)	2000-07-12	2003-05-13	Pharmacia & Upjohn Company	Heterocyle carboxamides as antiviral agents
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US7638522B2 (en)	2001-08-13	2009-12-29	Janssen Pharmaceutica N.V.	Salt of 4-[[4-[[4-(2-cyanoethenyl)-2,6-dimethylphenyl]amino]-2-pyrimidinyl]amino] benzonitrile
US8101629B2 (en)	2001-08-13	2012-01-24	Janssen Pharmaceutica N.V.	Salt of 4-[[4-[[4-(2-cyanoethenyl)-2,6-dimethylphenyl]amino]-2-pyrimidinyl]amino]benzonitrile
JP2005502685A (ja) *	2001-08-30	2005-01-27	ファルマシア・アンド・アップジョン・カンパニー	抗ウイルス剤としての４−チオキソ−４，７−ジヒドロ−チエノ［２，３−ｂ］ピリジン−５−カルボキシアミド
WO2003020728A1 (en) *	2001-08-30	2003-03-13	Pharmacia & Upjohn Company	4-THIOXO-4,7-DIHYDRO-THIENO[2,3-b]PYRIDINE-5-CARBOTHIOAMIDES AS ANTIVIRAL AGENTS
BR0215080A (pt) *	2001-12-20	2004-10-05	Osi Pharm Inc	Composto inibidores de lipase pancreática, sua sìntese e uso
AR038117A1 (es) *	2002-01-14	2004-12-29	Upjohn Co	Agentes antivirales derivados de la 4- oxo-4,7 -dihidrofuro [2,3-b]piridin-5-carboxamida
AR038118A1 (es)	2002-01-14	2004-12-29	Upjohn Co	Compuestos derivados de la bencinamida del acido 7-oxo-4,7-dihidrotien[2,3-b[piridin-6-carboxilico 3-sustituido que son utiles como antivirales
AR038294A1 (es) *	2002-01-14	2005-01-12	Upjohn Co	Oxotieno(3,2-b)piridincarboxamidas como agentes antivirales
AU2003222077A1 (en) *	2002-04-22	2003-11-03	Pharmacia And Upjohn Company	A trifluoroacetic acid process to prepare (2,3-b)pyridine intermediates
ES2422196T3 (es)	2002-08-09	2013-09-09	Janssen Pharmaceutica Nv	Procesos para la preparación de 4-4-4-(2-cianoetenil)-2,6-dimetilfenil)amino)-2-pirimidinil)aminobenzonitrilo
WO2004019940A1 (en) *	2002-08-30	2004-03-11	Pharmacia & Upjohn Company	Method of preventing or treating atherosclerosis or restenosis
US20040102473A1 (en) *	2002-08-30	2004-05-27	Wathen Michael W.	Method of preventing or treating atherosclerosis or restenosis
WO2004019932A1 (en) *	2002-08-30	2004-03-11	Pharmacia & Upjohn Company	Method of preventing or treating atherosclerosis or restenosis
AU2003262946A1 (en) *	2002-08-30	2004-03-19	Pharmacia And Upjohn Company	Method of preventing or treating atherosclerosis or restenosis
AU2003269950A1 (en) *	2002-09-04	2004-03-29	Pharmacia & Upjohn Company Llc	Heteroaryl-ethanolamine derivatives as antiviral agents
WO2004022566A1 (en) *	2002-09-04	2004-03-18	Pharmacia & Upjohn Company Llc	4-OXO-4,7-DIHYDROTHIENO[2,3-b]PYRIDINE-5-CARBOXAMIDES AS ANTIVIRAL AGENTS
US20040116464A1 (en) *	2002-09-04	2004-06-17	Schnute Mark E.	Aryl-ethanolamine derivatives as antiviral agents
AU2003304151A1 (en) *	2002-09-04	2005-01-21	Pharmacia And Upjohn Company	Heteroaryl-ethanolamine derivatives as antiviral agents
WO2005003140A1 (en) *	2003-07-02	2005-01-13	Pharmacia & Upjohn Company Llc	4-oxo-4,7-dihydrothieno[2,3-b]pyridine-5-carboxamides as antiviral agents
US20070208015A1 (en) *	2004-04-13	2007-09-06	Astex Therapeutics, Ltd.	5-Morpholinylmethylthiophenyl Pharmaceutical Compounds As P38 MAP Kinase Modulators
SE0401578D0 (sv)	2004-06-18	2004-06-18	Active Biotech Ab	Novel compounds
WO2006093518A2 (en) *	2004-06-25	2006-09-08	Apath, Llc	Thienyl compounds for treating virus-related conditions
WO2010099166A1 (en) *	2009-02-27	2010-09-02	Siga Technologies, Inc.	Thienopyridine derivatives for the treatment and prevention of dengue virus infections
MX385975B (es)	2016-02-16	2025-03-18	Univ Vanderbilt	Moduladores alostéricos positivos del receptor de acetilcolina muscarínico m1.
US10899759B2 (en)	2016-09-30	2021-01-26	Vanderbilt University	Positive allosteric modulators of the muscarinic acetylcholine receptor M1
CN112996789A (zh)	2018-09-12	2021-06-18	诺华股份有限公司	抗病毒吡啶并吡嗪二酮化合物
AU2020353055B2 (en)	2019-09-26	2024-03-07	Gilead Sciences, Inc.	Antiviral pyrazolopyridinone compounds
CN115073489B (zh) *	2021-03-15	2023-11-28	同济大学	一种噻吩骈吡啶酮类化合物、制备方法及一种抗真菌药物
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2000
- 2000-03-07 NZ NZ513758A patent/NZ513758A/en unknown
- 2000-03-07 DK DK00913786T patent/DK1159279T3/da active
- 2000-03-07 BR BR0008804-8A patent/BR0008804A/pt not_active IP Right Cessation
- 2000-03-07 EP EP00913786A patent/EP1159279B1/en not_active Expired - Lifetime
- 2000-03-07 HK HK02107054.6A patent/HK1045518A1/zh unknown
- 2000-03-07 CZ CZ20013028A patent/CZ20013028A3/cs unknown
- 2000-03-07 US US09/521,027 patent/US6239142B1/en not_active Expired - Fee Related
- 2000-03-07 IL IL14500500A patent/IL145005A0/xx unknown
- 2000-03-07 PL PL00350651A patent/PL350651A1/xx unknown
- 2000-03-07 PT PT00913786T patent/PT1159279E/pt unknown
- 2000-03-07 ES ES00913786T patent/ES2184705T3/es not_active Expired - Lifetime
- 2000-03-07 DE DE60000611T patent/DE60000611T2/de not_active Expired - Fee Related
- 2000-03-07 CN CN00806238A patent/CN1347417A/zh active Pending
- 2000-03-07 AU AU35162/00A patent/AU759875B2/en not_active Ceased
- 2000-03-07 KR KR1020017011447A patent/KR20010102543A/ko not_active Withdrawn
- 2000-03-07 AT AT00913786T patent/ATE226208T1/de not_active IP Right Cessation
- 2000-03-07 SK SK1258-2001A patent/SK12582001A3/sk unknown
- 2000-03-07 EA EA200100955A patent/EA003607B1/ru not_active IP Right Cessation
- 2000-03-07 HU HU0200324A patent/HUP0200324A3/hu unknown
- 2000-03-07 JP JP2000604046A patent/JP2002539130A/ja active Pending
- 2000-03-07 WO PCT/US2000/005937 patent/WO2000053610A2/en not_active Application Discontinuation
- 2000-03-07 CA CA002366609A patent/CA2366609A1/en not_active Abandoned
- 2000-03-09 TW TW089104265A patent/TWI222451B/zh not_active IP Right Cessation
2001
- 2001-04-02 US US09/824,334 patent/US6495683B2/en not_active Expired - Fee Related
- 2001-08-31 ZA ZA200107255A patent/ZA200107255B/en unknown
- 2001-09-07 NO NO20014363A patent/NO20014363L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
ES2184705T3 (es)	2003-04-16
EA200100955A1 (ru)	2002-02-28
NZ513758A (en)	2001-09-28
US6495683B2 (en)	2002-12-17
DE60000611D1 (en)	2002-11-21
US20020006937A1 (en)	2002-01-17
CZ20013028A3 (cs)	2002-03-13
PL350651A1 (en)	2003-01-27
IL145005A0 (en)	2002-06-30
EA003607B1 (ru)	2003-06-26
TWI222451B (en)	2004-10-21
NO20014363L (no)	2001-11-08
HK1045518A1 (zh)	2002-11-29
WO2000053610A3 (en)	2001-01-25
AU3516200A (en)	2000-09-28
WO2000053610A2 (en)	2000-09-14
ATE226208T1 (de)	2002-11-15
HUP0200324A3 (en)	2003-07-28
US6239142B1 (en)	2001-05-29
KR20010102543A (ko)	2001-11-15
CN1347417A (zh)	2002-05-01
AU759875B2 (en)	2003-05-01
BR0008804A (pt)	2002-04-16
EP1159279A2 (en)	2001-12-05
HUP0200324A2 (en)	2002-06-29
NO20014363D0 (no)	2001-09-07
JP2002539130A (ja)	2002-11-19
ZA200107255B (en)	2002-12-02
DE60000611T2 (de)	2003-06-26
DK1159279T3 (da)	2003-02-17
SK12582001A3 (sk)	2002-02-05
CA2366609A1 (en)	2000-09-14
EP1159279B1 (en)	2002-10-16

Publication	Publication Date	Title
PT1159279E (pt)	2003-02-28	4-oxo-4,7-di-hidrotieno¬2,3-b\|piridino-5-carboxamidas como agentes antivirais
AP1753A (en)	2007-07-18	Thiophene derivatives as antiviral agents for flavvivirus infection
BG108268A (en)	2005-04-30	Pyrazolopyrimidines as therapeutic agents
SE9903760D0 (sv)	1999-10-18	New compounds
WO2001019829A3 (en)	2001-09-27	Pyrazolopyrimidines as therapeutic agents
TR200200579T2 (tr)	2002-12-23	Amino-tirazolpiridin türevleri.
SE9900100D0 (sv)	1999-01-15	New compounds
AU2002246728A1 (en)	2002-08-28	Carboline derivatives
TR200201205T2 (tr)	2002-08-21	N-ikame edilmiş karbamoiloksialkil-azolyum türevleri.
ATE339409T1 (de)	2006-10-15	Trizyklische verbindungen
AU2002213421A1 (en)	2002-04-15	Condensed pyridoindole derivatives
AU2002249890A1 (en)	2002-08-28	Carboline derivatives
NO20055510L (no)	2006-01-20	2-alkynyl- og 2-alkenylpyrazolo [4,3-E]-1,2,4-triazolo-[1,5-C]-pyrimidin-adenosin A2A-reseptorantagonister
PE20030061A1 (es)	2003-02-08	1-biaril-1,8-naftiridin-4-ona como inhibidores de fosfodiesterasa-4
WO2003059878A3 (en)	2003-12-04	Thieno (3, 2-b) pyridones as antiviral compounds
MXPA04006041A (es)	2004-09-27	Antivirales de piridoquinoxalina.
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WO2003059911A3 (en)	2004-01-22	4-OXO-4, 7-DIHYDROFURO[2,3-b]PYRIDINE-5-CARBOXAMIDE ANTIVIRAL AGENTS
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BR0211214A (pt)	2004-07-13	4-tioxo-4,7-dihidro-tieno [2,3-b]piridina-5-carboxamidas como agentes antivirais
BR0211557A (pt)	2004-07-13	Compostos de 4-tioxo-4,7-dihidro-tieno[2,3-b]piridina-5-carbotioamid as como agentes antivirais, contosições e seus usos
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