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WO1993002660A1 - Emulsifiants concentres - Google Patents

Emulsifiants concentres Download PDF

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Publication number
WO1993002660A1
WO1993002660A1 PCT/EP1992/001673 EP9201673W WO9302660A1 WO 1993002660 A1 WO1993002660 A1 WO 1993002660A1 EP 9201673 W EP9201673 W EP 9201673W WO 9302660 A1 WO9302660 A1 WO 9302660A1
Authority
WO
WIPO (PCT)
Prior art keywords
alcohols
emulsifier
emulsifier concentrates
concentrates
alcohol
Prior art date
Application number
PCT/EP1992/001673
Other languages
German (de)
English (en)
Inventor
Achim Ansmann
Willi Breitzke
Axel Böttcher
Original Assignee
Henkel Kommanditgesellschaft Auf Aktien
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Henkel Kommanditgesellschaft Auf Aktien filed Critical Henkel Kommanditgesellschaft Auf Aktien
Priority to EP92916196A priority Critical patent/EP0596953A1/fr
Priority to JP5503226A priority patent/JPH06509740A/ja
Publication of WO1993002660A1 publication Critical patent/WO1993002660A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/28—Steroids, e.g. cholesterol, bile acids or glycyrrhetinic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/04—Dispersions; Emulsions
    • A61K8/06—Emulsions
    • A61K8/064—Water-in-oil emulsions, e.g. Water-in-silicone emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34—Alcohols
    • A61K8/342—Alcohols having more than seven atoms in an unbroken chain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/925—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of animal origin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/20—Chemical, physico-chemical or functional or structural properties of the composition as a whole
    • A61K2800/26—Optical properties
    • A61K2800/262—Transparent; Translucent

Definitions

  • the invention relates to a clear, liquid, at temperatures of 10 to 35 ° C. stable emulsifier concentrate based on sterols and / or wool wax alcohols and branched, saturated alcohols with 16 to 20 carbon atoms.
  • Sterols and wool wax alcohols are known auxiliaries for the production of cosmetic and pharmaceutical preparations.
  • they are used for the production of water-in-oil and oil-in-water emulsions, which are commercially available, for example, in the form of creams.
  • Commercial emulsifier concentrates which contain sterols or wool wax alcohols in a carrier consisting of paraffin oil are frequently used to produce such preparations.
  • such concentrates are cloudy at normal temperature and must be stirred and heated evenly before further processing.
  • the emulsifier concentrates according to the invention are in a clear, liquid form in a wide temperature range from 10 to 35 ° C. This means a considerable improvement over the conventional emulsifier concentrates based on sterols or wool wax alcohols in a mineral oil carrier, since the latter products are only in a clear form at higher temperatures.
  • the stars to be used according to the invention are steroids in which there is a hydroxyl group on the third carbon atom of the steroid structure and which are therefore chemically attributable to the alcohols.
  • the steroids occur in all animal and plant cells. According to their occurrence, they are divided into zoosterols, for example cholesterol, and phytosterols, which are predominantly found in higher plants.
  • wool wax alcohols are understood to mean complex mixtures of sterols and aliphatic alcohols from wool wax.
  • Suitable branched, saturated alcohols (B) are 2-hexyldecanol, 2-0ctyldodecanol or other branched, saturated alcohols having 16 to 20 carbon atoms.
  • e.g. 2- Hexyldecanol which is sold by the applicant under the name Eutanol G 16.
  • those emulsifier concentrates according to the invention in which the alcohol (B) is 2-octyldodecanol and are marketed by the applicant under the name Eutanol G are particularly well suited.
  • the emulsifier concentrates according to the invention can advantageously be used for the production of cosmetic or pharmaceutical preparations. They are particularly suitable for the preparation of preparations in the form of emulsions, preferably of the water-in-oil type.
  • the cosmetic or pharmaceutical emulsions produced on the basis of the emulsifier concentrates according to the invention are distinguished in particular by good storage stability. Storage stability means that after several months of storage the emulsions show no signs of separation or creaming and that the consistency is almost unchanged; This means in particular that the viscosity of the emulsions based on the emulsifier concentrates according to the invention remains approximately constant in the course of storage.
  • Croda CB 3896 Lanolin alcohols in mineral oil (Croda / Nettetal)
  • Amerchol L-101 Lanolin alcohols in mineral oil (Amerchol Europe / Vi-Ivorde-Belgium)
  • Lameform ( R ) TGI triglycerol diisostearate (company Henkel / Düsseldorf)
  • Emerv HP-2050 anhydrous lanolin according to DAB 9: mixture of esters, diesters and hydroxyesters of high molecular weight lanolin alcohols and lanolin fatty acids (company Henkel / Düsseldorf)
  • Monomuls ( R ) 90-0 18 oleic acid monoglyceride, molecularly distilled (company Henke1 / Düsse1dorf) 1.2.5. Oils
  • Myritol ( R ) 318 caprylic / capric acid triglyceride (company Henkel / Düsseldorf)
  • Vaseline Vaseline-DAB 9 (Riedel de Haen)
  • Permul ⁇ in ( R ) 3224 microcrystalline wax (A. Schmidt successor / -
  • Germall ( R ) 115 Idazolidinyl urea used as a preservative (Che ag / Frankfurt)
  • compositions and the turbidity behavior of the emulsifier concentrates EK 1 and EK 2 according to the invention and the comparisons EK 3 and EK 4 are summarized in Table 1.
  • This table shows that the concentrates according to the invention are in clear, liquid form over a wide temperature range, while the commercial comparisons in this range are only available in cloudy form.
  • Water-in-oil emulsions were prepared on the basis of concentrates EK 1 to EK 3, the compositions of which can be found in Table 2.
  • the emulsifier concentrates, co-emulsifiers, oils and consistency agents were combined at room temperature and heated to 75 ° C. with stirring. Water and the other auxiliaries were then introduced at this temperature with stirring. The emulsions thus obtained were cooled to about 35 ° C. and homogenized by further stirring. After further cooling to 20 ° C 93/02660
  • Viscosity of examples B1 and B3 according to the invention and comparisons VI and V2 measured using a Brookfield viscometer (Helipath) using spindle C at 5 rpm. The emulsions were then stored at room temperature for 12 weeks and the viscosities were determined again. The results of these measurements are summarized in Table 3.
  • Table 3 shows that the viscosity of the water-in-oil emulsions based on the emulsifier concentrates according to the invention changes over the course of the 93/02660 8 -

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Birds (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Emergency Medicine (AREA)
  • Dispersion Chemistry (AREA)
  • Dermatology (AREA)
  • Zoology (AREA)
  • Cosmetics (AREA)
  • Medicinal Preparation (AREA)
  • Colloid Chemistry (AREA)
  • Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)

Abstract

Des émulsifiants concentrés contiennent (A) 7 à 15 % en poids d'un alcool sélectionné dans le groupe des stérols et des alcools de graisse de laine: (B) 85 à 93 % en poids d'un alcool saturé à chaîne ramifiée ayant 16 à 20 atomes de C. Ces émulsifiants concentrés sont translucides et liquides et ne se troublent pas à des températures comprises entre 10 et 35 °C. On peut les utiliser avantageusement pour préparer des compositions cosmétiques et pharmaceutiques.
PCT/EP1992/001673 1991-07-31 1992-07-22 Emulsifiants concentres WO1993002660A1 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP92916196A EP0596953A1 (fr) 1991-07-31 1992-07-22 Emulsifiants concentres
JP5503226A JPH06509740A (ja) 1991-07-31 1992-07-22 乳化剤濃厚物

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4125332A DE4125332A1 (de) 1991-07-31 1991-07-31 Emulgatorkonzentrat
DEP4125332.9 1991-07-31

Publications (1)

Publication Number Publication Date
WO1993002660A1 true WO1993002660A1 (fr) 1993-02-18

Family

ID=6437391

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP1992/001673 WO1993002660A1 (fr) 1991-07-31 1992-07-22 Emulsifiants concentres

Country Status (4)

Country Link
EP (1) EP0596953A1 (fr)
JP (1) JPH06509740A (fr)
DE (1) DE4125332A1 (fr)
WO (1) WO1993002660A1 (fr)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2807323A1 (fr) * 2000-04-10 2001-10-12 Oreal Composition, notamment cosmetique, renfermant un steroide et un 2-alkyl alcanol ou un ester
WO2003035025A1 (fr) * 2001-07-10 2003-05-01 Cognis Japan Ltd. Composition a base d'huile contenant des sterols
EP1347734B2 (fr) † 2000-12-15 2009-07-29 Merz Pharma GmbH & Co. KGaA Huiles pour la peau formant des vesicules et contenant des emulsifiants eau dans l'huile presentant un equilibre hydrophile-lipophile egal a 2-5,9, leur procede de preparation et leur utilisation
US9493725B2 (en) 2014-09-08 2016-11-15 The Procter & Gamble Company Detergent compositions containing a predominantly C15 alkyl branched surfactant
US9493726B2 (en) 2014-09-08 2016-11-15 The Procter & Gamble Company Detergent compositions containing a predominantly C15 branched alkyl alkoxylated surfactant

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19539429C1 (de) * 1995-10-24 1997-04-24 Kawes S L Wasser/Öl-Misch-Emulgator sowie dessen Verwendung in kosmetischen und pharmazeutischen Salben, Cremes, Lotionen, Seifen, Shampoos und Badezusätzen
US7217432B2 (en) * 2002-04-19 2007-05-15 Cognis Corporation Vegetable substitute for lanolin
US7220432B2 (en) * 2002-04-19 2007-05-22 Cognis Corporation Vegetable substitute for lanolin

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3422204A (en) * 1963-11-13 1969-01-14 Exxon Research Engineering Co Cosmetic composition containing lanolin and hexadecyl alcohol
EP0034126A1 (fr) * 1980-01-25 1981-08-19 Luigi Maggesi Compositions cosmétiques et dermatologiques pour le rasage
US4853222A (en) * 1986-08-01 1989-08-01 Intercos Italiana S.P.A. Ointment for concealing skin blemishes and scars

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3422204A (en) * 1963-11-13 1969-01-14 Exxon Research Engineering Co Cosmetic composition containing lanolin and hexadecyl alcohol
EP0034126A1 (fr) * 1980-01-25 1981-08-19 Luigi Maggesi Compositions cosmétiques et dermatologiques pour le rasage
US4853222A (en) * 1986-08-01 1989-08-01 Intercos Italiana S.P.A. Ointment for concealing skin blemishes and scars

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2807323A1 (fr) * 2000-04-10 2001-10-12 Oreal Composition, notamment cosmetique, renfermant un steroide et un 2-alkyl alcanol ou un ester
US6486147B2 (en) 2000-04-10 2002-11-26 L'oreal Cosmetic composition containing a steroid and a 2-alkylalkanol or an ester thereof
EP1347734B2 (fr) † 2000-12-15 2009-07-29 Merz Pharma GmbH & Co. KGaA Huiles pour la peau formant des vesicules et contenant des emulsifiants eau dans l'huile presentant un equilibre hydrophile-lipophile egal a 2-5,9, leur procede de preparation et leur utilisation
WO2003035025A1 (fr) * 2001-07-10 2003-05-01 Cognis Japan Ltd. Composition a base d'huile contenant des sterols
US9493725B2 (en) 2014-09-08 2016-11-15 The Procter & Gamble Company Detergent compositions containing a predominantly C15 alkyl branched surfactant
US9493726B2 (en) 2014-09-08 2016-11-15 The Procter & Gamble Company Detergent compositions containing a predominantly C15 branched alkyl alkoxylated surfactant

Also Published As

Publication number Publication date
JPH06509740A (ja) 1994-11-02
DE4125332A1 (de) 1993-02-04
EP0596953A1 (fr) 1994-05-18

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