WO1997015672A1 - Dna containing novel gene - Google Patents
Dna containing novel gene Download PDFInfo
- Publication number
- WO1997015672A1 WO1997015672A1 PCT/JP1996/003127 JP9603127W WO9715672A1 WO 1997015672 A1 WO1997015672 A1 WO 1997015672A1 JP 9603127 W JP9603127 W JP 9603127W WO 9715672 A1 WO9715672 A1 WO 9715672A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- dna
- dnas
- novel gene
- endothelial cells
- vascular endothelial
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
A DNA involving at least the peptide code region of a full-length DNA characterized by the restriction enzyme cleavage sites specified in Fig. 1. This DNA contains a novel gene which is expressed depending on the shear stress on vascular endothelial cells. Use of the DNA makes it possible to judge whether or not vascular endothelial cells are in the normal physiological environment with the application of the shear stress which has never been clarified so far. Also disclosed are a DNA involving a part of the DNA described above; a DNA hybridizable with the part of the above DNA; DNAs complementary to these DNAs; RNAs complementary to these DNAs; replicable recombinant DNAs constructed by integrating these DNAs into replicable expression vectors in such a manner as to allow the replication; peptides encoded by the above DNAs; and antibodies capable of binding to these peptides.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP7/277781 | 1995-10-25 | ||
| JP27778195 | 1995-10-25 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| WO1997015672A1 true WO1997015672A1 (en) | 1997-05-01 |
Family
ID=17588224
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PCT/JP1996/003127 WO1997015672A1 (en) | 1995-10-25 | 1996-10-25 | Dna containing novel gene |
Country Status (1)
| Country | Link |
|---|---|
| WO (1) | WO1997015672A1 (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1999064021A1 (en) * | 1998-06-11 | 1999-12-16 | Smithkline Beecham Corporation | hCEPR RECEPTOR |
-
1996
- 1996-10-25 WO PCT/JP1996/003127 patent/WO1997015672A1/en active Application Filing
Non-Patent Citations (5)
| Title |
|---|
| BIOCHIM. BIOPHYS. ACTA, Vol. 1219, No. 1, 1994, WANG D.Z. et al., "Molecular Cloning and Sequence Analysis of Rat Bradykinin B2 Receptor Gene", pages 171-174. * |
| JOURNAL OF BIOLOGICAL CHEMISTRY, Vol. 269, No. 28, 1994, SUZUKI H. et al., "The N Terminus of Interleukin-8 (IL-8) Receptor Confers High Affinity Binding to Human IL-8", pages 18263-18266. * |
| SCIENCE, Vol. 253, 1991, HOLMES W.E. et al., "Structure and Functional Expression of a Human Interleukin-8 Receptor", pages 1278-1280. * |
| SCIENCE, Vol. 253, 1991, MURPHY P.M. et al., "Cloning of Complementary DNA Encoding a Functional Human Interleukin-8 Receptor", pages 1280-1283. * |
| SCIENCE, Vol. 257, 1992, PENG LIANG et al., "Differential Display of Eukaryotic Messenger RNA by Means of the Polymerase Chain Reaction", pages 967-971. * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1999064021A1 (en) * | 1998-06-11 | 1999-12-16 | Smithkline Beecham Corporation | hCEPR RECEPTOR |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| EP1439226A3 (en) | A nucleic acid antisense sequence to a polynucleotide encoding a polypeptide having heparanese activity | |
| CA2294516A1 (en) | Ikk-.beta. proteins, nucleic acids and methods | |
| DE69635864D1 (en) | RECOMBINANT RNA REPLICASE OF HEPATITIS C VIRUS | |
| EP1164195A3 (en) | Adeno-associated virus with inverted terminal repeat sequences as promoter | |
| WO1998012328A3 (en) | Human bad polypeptides, encoding nucleic acids and methods of use | |
| CA2263889A1 (en) | P-selectin ligand proteins | |
| WO1999066025A3 (en) | Mtbx protein and nucleic acid molecules and uses therefor | |
| WO2001072976A3 (en) | 32142, 21481, 25964, 21686, novel human dehydrogenase molecules and uses therefor | |
| WO2001000806A3 (en) | Dna's encoding proteins with signal peptides | |
| WO2001025438A3 (en) | Ifn-alpha homologues | |
| EP0828003A3 (en) | Human serine protease | |
| GB9722320D0 (en) | Human cell cycle checkpoint proteins | |
| CA2280290A1 (en) | Netrin receptors | |
| CA2252493A1 (en) | .beta.-galactoside - .alpha. 2,6-sialyltransferase gene | |
| EP1005539A4 (en) | IKK-$g(a) PROTEINS, NUCLEIC ACIDS AND METHODS | |
| DE69732847D1 (en) | ENDOTHEL SPECIFIC EXPRESSION UNDER INFLUENCE OF EPCR CONTROL ELEMENTS | |
| WO1995030001A3 (en) | Novel p-selectin ligand protein | |
| WO2000019988A8 (en) | NOVEL Th2-SPECIFIC MOLECULES AND USES THEREOF | |
| WO1997014797A3 (en) | Cystatin m, a novel cysteine proteinase inhibitor | |
| WO1994025606A3 (en) | Recombinant alanine racemase and gapdh from tolypocladium | |
| WO1997015672A1 (en) | Dna containing novel gene | |
| AU7508694A (en) | Novel tyrosine kinase | |
| WO1998002456A3 (en) | Human c-type lectin | |
| WO2000012544A3 (en) | Novel irap-bp polypeptide and nucleic acid molecules and uses therefor | |
| WO1995013386A3 (en) | Tyrosinase-activator protein fusion enzyme |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| AK | Designated states |
Kind code of ref document: A1 Designated state(s): US |
|
| AL | Designated countries for regional patents |
Kind code of ref document: A1 Designated state(s): AT BE CH DE DK ES FI FR GB GR IE IT LU MC NL PT SE |
|
| DFPE | Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101) | ||
| 121 | Ep: the epo has been informed by wipo that ep was designated in this application | ||
| 122 | Ep: pct application non-entry in european phase |