WO1997036560A1 - Dispositif produisant du froid, pour usage therapeutique - Google Patents
Dispositif produisant du froid, pour usage therapeutique Download PDFInfo
- Publication number
- WO1997036560A1 WO1997036560A1 PCT/CA1997/000198 CA9700198W WO9736560A1 WO 1997036560 A1 WO1997036560 A1 WO 1997036560A1 CA 9700198 W CA9700198 W CA 9700198W WO 9736560 A1 WO9736560 A1 WO 9736560A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- heat exchange
- fluid
- chamber
- housing
- heat exchanger
- Prior art date
Links
- 238000002560 therapeutic procedure Methods 0.000 title description 10
- 239000012530 fluid Substances 0.000 claims abstract description 165
- 238000001816 cooling Methods 0.000 claims abstract description 98
- 238000004891 communication Methods 0.000 claims abstract description 32
- 238000010438 heat treatment Methods 0.000 claims abstract description 20
- 230000001225 therapeutic effect Effects 0.000 claims abstract description 6
- 239000007787 solid Substances 0.000 claims description 31
- 230000003134 recirculating effect Effects 0.000 claims description 22
- 239000007788 liquid Substances 0.000 claims description 14
- 238000007789 sealing Methods 0.000 claims description 5
- 239000004033 plastic Substances 0.000 claims description 4
- 230000000295 complement effect Effects 0.000 claims 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract description 49
- 239000003507 refrigerant Substances 0.000 abstract description 17
- 238000011282 treatment Methods 0.000 abstract description 5
- 238000005086 pumping Methods 0.000 abstract description 4
- 208000014674 injury Diseases 0.000 abstract description 3
- 230000006378 damage Effects 0.000 abstract description 2
- 208000027418 Wounds and injury Diseases 0.000 abstract 1
- 238000012546 transfer Methods 0.000 description 11
- 208000002193 Pain Diseases 0.000 description 8
- 230000017525 heat dissipation Effects 0.000 description 5
- 238000010586 diagram Methods 0.000 description 3
- 230000009471 action Effects 0.000 description 2
- 229910052782 aluminium Inorganic materials 0.000 description 2
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 2
- 239000002826 coolant Substances 0.000 description 2
- 239000000945 filler Substances 0.000 description 2
- 230000006872 improvement Effects 0.000 description 2
- 238000003754 machining Methods 0.000 description 2
- 229910052751 metal Inorganic materials 0.000 description 2
- 239000002184 metal Substances 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 238000011160 research Methods 0.000 description 2
- 125000006850 spacer group Chemical group 0.000 description 2
- 230000008733 trauma Effects 0.000 description 2
- 208000000112 Myalgia Diseases 0.000 description 1
- XUIMIQQOPSSXEZ-UHFFFAOYSA-N Silicon Chemical compound [Si] XUIMIQQOPSSXEZ-UHFFFAOYSA-N 0.000 description 1
- 206010066371 Tendon pain Diseases 0.000 description 1
- 238000001467 acupuncture Methods 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 239000000110 cooling liquid Substances 0.000 description 1
- 239000000498 cooling water Substances 0.000 description 1
- 230000006735 deficit Effects 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000002635 electroconvulsive therapy Methods 0.000 description 1
- 238000001704 evaporation Methods 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 238000007710 freezing Methods 0.000 description 1
- 230000008014 freezing Effects 0.000 description 1
- 230000002631 hypothermal effect Effects 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 239000011499 joint compound Substances 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 238000012544 monitoring process Methods 0.000 description 1
- 210000003205 muscle Anatomy 0.000 description 1
- 208000013465 muscle pain Diseases 0.000 description 1
- 230000037361 pathway Effects 0.000 description 1
- 230000002572 peristaltic effect Effects 0.000 description 1
- 238000000053 physical method Methods 0.000 description 1
- 230000002035 prolonged effect Effects 0.000 description 1
- 238000005057 refrigeration Methods 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 230000000284 resting effect Effects 0.000 description 1
- 229910052710 silicon Inorganic materials 0.000 description 1
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- 230000003068 static effect Effects 0.000 description 1
- 230000008961 swelling Effects 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 239000008399 tap water Substances 0.000 description 1
- 235000020679 tap water Nutrition 0.000 description 1
- 230000002123 temporal effect Effects 0.000 description 1
- 238000007669 thermal treatment Methods 0.000 description 1
- 230000000699 topical effect Effects 0.000 description 1
- 238000002646 transcutaneous electrical nerve stimulation Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
- A61F7/02—Compresses or poultices for effecting heating or cooling
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
- F25B—REFRIGERATION MACHINES, PLANTS OR SYSTEMS; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS
- F25B21/00—Machines, plants or systems, using electric or magnetic effects
- F25B21/02—Machines, plants or systems, using electric or magnetic effects using Peltier effect; using Nernst-Ettinghausen effect
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
- A61F2007/0054—Heating or cooling appliances for medical or therapeutic treatment of the human body with a closed fluid circuit, e.g. hot water
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
- A61F2007/0054—Heating or cooling appliances for medical or therapeutic treatment of the human body with a closed fluid circuit, e.g. hot water
- A61F2007/0056—Heating or cooling appliances for medical or therapeutic treatment of the human body with a closed fluid circuit, e.g. hot water for cooling
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
- A61F7/007—Heating or cooling appliances for medical or therapeutic treatment of the human body characterised by electric heating
- A61F2007/0075—Heating or cooling appliances for medical or therapeutic treatment of the human body characterised by electric heating using a Peltier element, e.g. near the spot to be heated or cooled
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
- A61F7/007—Heating or cooling appliances for medical or therapeutic treatment of the human body characterised by electric heating
- A61F2007/0075—Heating or cooling appliances for medical or therapeutic treatment of the human body characterised by electric heating using a Peltier element, e.g. near the spot to be heated or cooled
- A61F2007/0076—Heating or cooling appliances for medical or therapeutic treatment of the human body characterised by electric heating using a Peltier element, e.g. near the spot to be heated or cooled remote from the spot to be heated or cooled
Definitions
- the present invention relates to devices for cold and/or hot therapy and devices for cooling and/or heating adjacent areas on a person for therapeutic purposes
- Pain abatement research is a major area of study which goes hand-in-hand with pain research itself
- pain is a symptom of an underlying malady or trauma so the presence and nature of the pain in these cases is sometimes essential in aiding awareness and the diagnosis of the underlying illness
- the abatement of pain has traditionally been effected using various external and internal treatments.
- external treatment include acupuncture, electro-shock treatment using transcutaneous electrical nerve stimulation (TENS), use of temperature such as application of hot or cold packs or topical application of cooling or heating formulations
- TENS transcutaneous electrical nerve stimulation
- Examples of internal, invasive treatments include drug treatments by oral administration or injection of freezing agents Where feasible, the external physical methods of alleviating pain are preferable over the invasive, internal techniques for obvious reasons
- Hot or cold to localized pain such as muscle or tendon pain to reduce swelling
- Hot water bottles and ice or cold packs are among the oldest and simplest devices for applying heat and cooling respectively
- Another type of device is the heating blanket that uses electrical resistive heaters for heating United States Patent No 4,094,357 discloses a heat transfer blanket which uses heat pipes coupled to heating/cooling systems
- United States Patent No. 5,269,369 teaches a body suit which utilizes a system of heat pipes to redistribute body heat for heating or cooling the person wearing the suit.
- United States Patent Nos 4,459,468 issued to Bailey discloses a temperature control fluid circulating system provided with a thermal blanket and a large refrigerant reservoir using thermoelectric units inserted directly into the reservoir to heat and cool the refrigerant in the reservoir.
- United States Patent No. 3,154,926 issued to Hirschhom teaches a cooling blanket with a coolant reservoir with substantially all of one side of the reservoir in contact with thermoelectric Peltier units to cool the liquid in the reservoir.
- Patent No. 4,523,594 issued to Kuznetz discloses a heat exchange jacket that can be used in an open loop mode or a closed loop mode.
- the jacket In the open loop mode the jacket is connected to a hot or cold water faucet in a hospital or home while in the closed loop mode a thermoelectric device is used to heat/cool water in the reservoir which is in series with a pump.
- No. 3,967,627 issued to Brown is directed to a hot/cold applicator system utilizing a peristaltic pump in series with a patient blanket, a fluid reservoir and a heat exchanger for heating/cooling the fluid.
- a drawback to these types of devices is poor efficiency of cooling the refrigerant since essentially the entire volume of coolant contained in the reservoir must be cooled.
- the device includes a fluid pump located between a heat exchanger and a reservoir and a double impeller pump with an upper impeller connected in series with the reservoir and the hot side of a thermoelectric unit and a lower impeller pump connected in series with the cold side of the thermoelectric unit and the patient blanket.
- United States Patent No. 4,170, 998 to Sauder is directed to a portable cooling apparatus for cooling a limb of a patient which includes a compressor and evaporator for condensing and evaporating the refrigerant.
- a drawback to this type of system and others like it is that they are quite bulky and awkward since they use large fluid pumps between the heat exchanger and the blanket or pad being heated or cooled.
- Some of the systems employ condensers, refrigerants and evaporator coils which are also bulky, awkward and of limited mobility. It would therefore be advantageous to provide compact and economical devices for thermal treatment of maladies or trauma of the body provided with an efficient method of rapidly cooling/heating the refrigerant.
- the present invention provides a portable heat exchange device for heat exchange therapy of a patient.
- the device comprises a heat exchange pad means having at least one fluid inlet and one fluid outlet through which a fluid exchange medium may be circulated through the pad means.
- the device includes a heat exchange module including a first housing having a fluid recirculation inlet and a fluid recirculation outlet and conduit means communicating the recirculating fluid inlet and the recirculating fluid with the fluid outlet and fluid inlet, respectively, of the pad means.
- a first chamber is located within the first housing in fluid communication with a source of fluid heat exchange medium and the fluid recirculation inlet and fluid recirculation outlet.
- the first housing has at least one opening into the first chamber, and one of either a heat source and a heat sink having an inner surface is mounted within the opening with the inner surface in heat exchange relationship with the fluid heat exchange medium within the first chamber.
- the device includes means for circulating the fluid heat exchange medium through the first chamber so as to contact the inner surface and to convey the fluid heat exchange medium to the recirculating fluid outlet to the pad means
- thermoelect ⁇ c Peltier unit comprising the inner surface and having an opposed outer surface
- a portable therapeutic heat exchange device comprising heat exchange pad means having at least one fluid inlet and one fluid outlet through which a fluid heat exchange medium may be circulated through the pad means
- the heat exchange device includes a heat exchange module including a housing provided with a fluid recirculation inlet and a fluid recirculation outlet and conduit means communicating the recirculating fluid inlet and the recirculating fluid outlet with the fluid outlet and fluid inlet respectively, of the heat exchange pad means
- the housing includes a chamber in flow communication with a source of fluid heat exchange medium and the fluid recirculation inlet and the fluid recirculation outlet
- the housing includes at least one opening that opens into the chamber and a thermoelectric Peltier unit having a heated outer surface and a cooled inner surface is mounted within the opening with the inner surface in heat exchange relationship with the fluid heat exchange medium within the chamber
- the device includes means for circulating the fluid heat exchange medium through the chamber so as to contact the cooled inner surface and to convey the
- the device includes a heat exchanger with a heat exchanger chamber, a thermally conducting solid portion adjacent to the chamber and a finned portion extending from the solid portion
- the cooling module is seated in the heat exchanger chamber with the outer heated surface thermally contacted to the solid portion
- a compact heat exchange device for cooling and/or heating a heat exchange fluid
- the device comprises a heat exchange module including a first housing having a fluid recirculation inlet and a fluid recirculation outlet, a first chamber within the first housing in fluid communication with the fluid recirculation inlet and the fluid recirculation outlet.
- the first housing is provided with at least one opening in the into the first chamber and a thermoelectric Peltier unit having a first surface and an opposed second surface is mounted within the at least one opening and is in liquid tight sealing relationship with the housing with the first surface in heat exchange relationship with a fluid heat exchange medium within the first chamber.
- the device includes a first pump with a first impeller, the first pump being attached to the first housing in communication with the fluid recirculation outlet to pump for circulating the heat exchange fluid through the first chamber so as to contact the first surface and to convey the heat exchange fluid through the recirculating fluid outlet.
- the present invention also provides heat exchanger comprising a thermally conducting solid portion having a heat exchanger chamber with at least one surface adapted to receive thereagainst and object to be cooled.
- the heat exchanger includes a thermally conducting finned portion in thermal contact with the thermally conducting solid portion.
- the heat exchanger comprises a plurality of heat exchange plates assembled in a stacked relationship wherein each heat exchanger plate has a central section and at least one fin portion extending from the central section.
- the central section of each heat exchanger plate has an aperture and the central sections of adjacent heat exchange plates are partially overlapped to form the thermally conducting solid portion with the apertures in registration to define walls of the heat exchanger chamber.
- the fin portions of adjacent plates in the stack are spaced by dimples located on each fin portion of the plate.
- Figure 1 is a perspective view of an apparatus for heating and cooling constructed in accordance with the present invention
- Figure 2 is a cross sectional view along line 2-2 of Figure 1 ;
- Figure 3a is a top view of a heat exchanger forming part of the apparatus in Figure 1 ;
- Figure 3b is a sectional view along the line 3b-3b of Figure 3a;
- Figure 3c is an enlarged view of the circled portion of Figure 3b;
- Figure 4 is a top view of the structural member from which the heat exchanger of Figure 3a is constructed;
- Figure 5 is an assembly view of a cooling module forming part of the present invention;
- Figure 6a is a sectional view along line 6a-6a of Figure 5;
- Figure 6b is a sectional view along line 6b-6b of Figure 5;
- Figure 7a is an exploded perspective view of the apparatus of Figure 1 ;
- Figure 7b is a perspective view of the cold therapy device of Figure 1 partially assembled
- Figure 8a is a sectional view along line 8a-8a of Figure 8b;
- Figure 8b is a top view of the water reservoir of Figure 7a;
- Figure 8c is an enlarged sectional view of the circled portion of
- Figure 9 is a sectional view along the line 9-9 of Figure 7b;
- Figure 10 is a diagrammatic illustration of the cold therapy device of Figure 1 ;
- Figure 11 is a flow diagram of the operating logic employed in the control circuit forming part of the cooling apparatus;
- Figure 12a is a perspective view of an alternative embodiment of a cooling chamber according to the present invention.
- Figure 12b is an elevational view of the cooling chamber of Figure 12a;
- Figure 12c is a bottom view of the cooling chamber of Figure 12a;
- Figure 13a is a bottom view of an alternative embodiment of a cooling unit according to the present invention.
- Figure 13b is a perspective view of the cooling unit of Figure 13a and associated heat exchanger, having a portion removed;
- Figure 14 is a bottom view of an alternative embodiment of a cooling unit according to the present invention.
- Figure 15 is a perspective view of an alternative embodiment of a heat excnanger of the present cooling device.
- Figure 16 is a perspective view of another embodiment of a heat exchanger of the present cooling device.
- Figure 17 is a perspective view of another alternative embodiment of a heat exchanger of the present cooling device.
- Figure 18 is a top view of another alternative embodiment of a heat exchanger of the present cooling device;
- Figure 19 is a cross sectional view along the line 19-19 of Figure
- Figure 20 is a cross sectional view along the line 20-20 of Figure 18;
- Figure 21 is a sectional view, broken away, showing several plates in Figure 19 stacked to form a cooling chamber;
- Figure 22 is a perspective view of a ⁇ alternative embodiment of an apparatus for heating and cooling constructed in accordance with the present invention.
- Figure 23 a sectional view of a water pump forming part of the apparatus of Figure 22;
- Figure 24 is an exploded view of a portion of the fluid pump of Figure 22;
- Figure 25 is an assembly view of an alternative embodiment of a heating/cooling module constructed in accordance with the present invention
- Figure 26a is a cross sectional view taken along line 26a-26a in
- Figure 25 Figure 26b is an exploded view of the section of Figure 26a; Figure 26c is similar to Figure 26b showing the fluid flow path; Figure 27 shows the assembled cooling module of Figures 25; Figure 28 is a perspective view of a the cooling module of Figure 25 disassembled; and
- Figure 29 is a perspective view of part of the cooling module of Figure 26.
- Cooling apparatus 20 includes a heat exchanger 22 with a base plate 24 and four grommets 26 attached to base plate 24 to provide a support for the device.
- a housing 28 is mounted on top of heat exchanger 22 and is provided with a carrying handle 30 for carrying the assembled apparatus.
- Housing 28 includes a pair of spaced hooks 32, best seen in Figure 1 , disposed along one side of housing 28 for hooking the apparatus 20 onto a bed railing or wall rail beside a patient using the device.
- An on-off switch 38 and a cord 40 provide power to the apparatus.
- housing 28 encloses two power supplies 44 and a control circuit 46 mounted on top of the power supplies.
- Housing 28 encloses a reservoir 34 having a pop-top lid 36 for filling the reservoir.
- Heat exchanger 22 contains two cooling fans 50 one located on each side of a cooling chamber 52. Cooling module 56 is received into cooling chamber 52.
- heat exchanger 22 is constructed by overlapping alternating heat conducting plates 58, preferably aluminum, where all the elements are structurally identical. Four bolts 60 are used to secure the stack of elements 58 together.
- each heat conducting element 58 is has a triangular middle section 62 having a base 64 and elongate L-shaped frame members 68 extending from base 64. The middle section 62 encloses a rectangular aperture 66.
- Element 58 includes holes 70 at both ends of arms 68 in addition to holes 72 in the middle portion 62 through which bolts 60 are inserted to secure the assembled heat exchanger together.
- the end portions 68 are provided with dimples 74 extending upwardly out of the plane of plate 58 and dimples 76 extending downwardly in the opposite direction.
- a tab 78 extends outwardly from arm 68 and is provided with a notch 80.
- One of the triangular sections 62 is provided with a triangular protrusion having a notched apex 84.
- the stack of plates 58 is assembled as shown in Figure 3b so the dimples 74 and 76 line up as seen in the enlargement of Figure 3c.
- the chamber 52 ( Figure 3a) thereby formed is originally rectangular because all the apertures 66 ( Figure 4) are the same size.
- the tapered chamber 52 in Figure 3b is obtained by machining out the heat exchanger chamber so that the upper portion 88 of the chamber 52 is wider and tapers to the lower portion 90.
- the inner walls of 96 and 98 of tapered chamber 52 are essentially solid since the plates 58 are tightly compressed together before machining.
- the triangular portions 94 formed by the overlapping sections 62 of each plate 58 in the assembled heat exchanger form a thermally conducting solid portion and the elongate frame members 68 extending out from the solid portion form the finned portion of the exchanger with a gap between adjacent plates in the finned section due to dimples 74 and 76 acting as spacers.
- heat exchanger 22 when heat exchanger 22 is assembled from plates 58, notches 84 and 80 on each side of chamber 52 define a rectangular volume.
- the cooling fans 50 Figure 2 fit into these rectangular volumes.
- the solid triangular portions 94 provide excellent heat conduction away from walls 98 into the finned portion of the heat exchanger.
- the heat flow from chamber wall 98 into the finned portion of the heat exchanger is parallel to the surface of the plates thereby advantageously providing optimum heat transfer from wall 98 to the surface area for heat dissipation.
- the size of the solid portion of the heat exchanger is preferably kept to a minimum as it is required to conduct heat from the thermal contact surfaces to the finned portions.
- Cooling module 56 comprises a housing 110 that is tapered, best seen in Figure 6a.
- the taper of housing 110 substantially matches the angle of the taper of chamber 52 in heat exchanger 22, see Figure 3b.
- Housing 110 encloses a chamber 112 with opposed open sides with an O-ring groove 114 extending around the opening on each face.
- housing 110 includes passageways 116 and 118 into which spigots 120 and 122 respectively are inserted.
- spigots 120 and 122 may be formed with housing 110 as a unitary structure as shown in Figure 6b.
- passageway 118 is the fluid flow path back into chamber 112 from the cooled blanket and includes an upper wider channel 124 and a narrower lower channel
- Cooling module 56 is provided with a liquid pressure/flow sensor
- Pressure/flow sensor 132 having spaced conduits 134 and 136 inserted into passageways 128 and 130 respectively.
- Pressure/flow sensor 132 is placed in the flow circuit with the restriction between passageways 124 and 126 located between its inputs. The restriction creates a pressure difference across sensor 132 which indicates flow and no flow conditions.
- MPX11 and MPX12 produced by Motorola have been found to be quite adequate.
- Housing 110 is provided with a channel 142 in flow communication with chamber 112.
- a fitting 144 protruding from housing 110 is in flow communication with passageway 116 and is used for filling chamber 112 when the cooling module is assembled.
- Passageway 116 provides an air return line from chamber 112 to reservoir 34 so that air is displaced from chamber 112 into reservoir 34 as the chamber is being filled.
- thermoelectric unit 148 includes opposed surfaces 150 and 152 and a pair of wires 154 which are electrically connected to the control circuit 46 ( Figure 7a)
- a pair of groves 138 and 140 extend upwardly from O- ⁇ ng groove 114 and provide a channel for each of the electrical wires 154
- a liquid pump 160 is coupled to housing 110 with an O- ⁇ ng seal 161 and spring bracket 170 and the pump comprises a impeller shaft housing 162 in which an impeller 164 is housed
- the impeller housing 162 is inserted into passageway 142 and the pump is secured to the housing by means of the spring bracket 170 which is pivotally attached to the housing 110 and snaps over the upper end 168 of the pump
- pump motor 160 is coupled to housing 110 a portion of the impeller housing 162 and impeller
- water reservoir 34 is preferably moulded of a translucent plastic to allow viewing of the water or liquid level in the reservoir but which does not become unsightly as would a clear plastic after prolonged exposure to tap water Reservoir 34 has an opening 180 for filling with water or other heat exchange fluid
- a ⁇ air return line connection 182 is located at the top of the reservoir and an air line 196 is attached thereto at one end
- the reservoir 34 is provided with a downwardly extending section 184 spaced away from the outer wall containing the air return line connection 182 thereby defining a gap 194
- the air return line is protected from the reservoir being overfilled by an air pocket forming in gap 194 thus preventing water from filling the air return
- a filler spigot 188 is located on the bottom 190 of the reservoir and a filter 192 covers the outlet passageway, best seen in Figure 9
- a filler tube 198 is attached to spigot 188 at one end thereof
- Reservoir lid 36 is provided with several small holes 39 ( Figure 7a) which are small enough to resist water
- tube 198 is attached to spigot 144 ( Figure 5) located on the housing of cooling module 56 to provide a cooling liquid supply to the cooling unit from reservoir 34
- the other end of air line 196 is connected to air return spigot 120
- Hose 172 is connected to spigot 122 and provides the liquid return line from the cooling blanket Hose 174 is connected at one end to fitting 166 on pump 160 and the other end is connected to the cooling blanket thereby supplying liquid to the blanket 200 ( Figure 10)
- thermoelectric units 148 In operation, heat is extracted out of the fluid in chamber 112 by the two thermoelectric units 148 ( Figures 6a and 7a) Specifically, thermoelectric units 148 transfer the heat to heat exchanger 22 which dissipates the extracted heat into the air
- the two fans 50 are inserted in the heat sink 22 and force air over the surface of the fins 58 and facilitates the dissipation of the heat into the air
- the cold fluid from chamber 112 is circulated through a patient wrap 200 which is placed directly on the area of the patient to be treated
- the cold fluid is drawn up from the cooling chamber 112 by pump 160 and delivered to the wrap or cooling blanket 200 through tube 174
- the water returns from the blanket 200 to housing chamber 1 12 in cooling module 56 through the return tube return line 172
- Water reservoir 34 is provided with a reserve of fluid which ensures a full flow circuit to maximize performance and prevent damage to the apparatus
- Chamber 112 in the cooling module housing 110 has a volume substantially smaller than the fluid containing volume within reservoir 34
- Power to cooling apparatus 20 in Figure 1 a is controlled by on/off switch 38. When activated the device runs at maximum cooling. There are no user/operator adjustments on the units.
- the two power supplies 44 provide power to the control circuit and the control circuit in turn controls the thermoelectric modules 148, fans 50 and pump 160.
- the system is designed to maximize pump-motor life and provide the preset flow rate conditions (4.0 to 4.5 gallons per hour).
- control circuit 46 achieves this by monitoring pressure/flow sensor 132 and regulating the supply voltage to pump 160 to maintain water flow between cooling module 56 and patient blanket 200 without exceeding the maximum voltage limitations. Should the voltage remain at the maximum for longer than 3.0 minutes a clearing cycle is initiated. The pump voltage is switched on for 8 seconds at 5.5 volts and off for 1 second. This cycle continues until the flow returns to normal operating levels. Details of the operating logic are shown in the flow diagram in Figure 11.
- heat exchanger 22 conduct heat from the outer hot surfaces 152 of thermoelectric units 148 through the triangular shaped overlapping sections 94 and the heat is conducted into the fin sections having air gaps between adjacent fins to dissipate heat.
- heat exchanger 22 is provided with very efficient heat dissipation by designing the heat exchanger with similarly shaped plates which have an overlapping solid portion which very efficiently conducts heat from the thermoelectric units to the air cooled finned section.
- thermoelectric units 148 When tapered housing 110 with thermoelectric units 148 engaged against the open faces is inserted into chamber 52 with the thermoelect ⁇ c units engaged against the O-rings in housing 110, the matching tapered shape of chamber 52 acts to lock the cooling assembly in place and provides a tight fit which ensures good thermal contact between the cooling module and the heat exchanger.
- the outer surface 152 of thermoelectric units 148 are preferably coated with thermal joint compound prior to being inserted into chamber 52 to ensure good heat transfer between thermoelectric units 148 and heat exchanger 22
- FIGS 12a to 12c illustrate a triangular cooling chamber housing 202 with three thermoelectric units 148 and water inlet 204 and outlet 206
- FIGS. 13a and 13b illustrate a four-sided cooling chamber 210 provided with four thermoelect ⁇ c units 148 The corresponding heat exchanger
- Cooling chamber 212 is provided with four sections similar to sections 94 in heat sink 22 in Figure 3a to provide efficient heat transfer from cooling chamber 210 to the finned portion of the heat exchanger (not shown)
- Figure 14 illustrates an eight-sided cooling chamber 220 provided with eight thermoelectric units 148 These embodiments of the cooling chamber are advantageous for increasing cooling capacity
- the cooling units are tapered as are the corresponding heat exchanger chambers in the heat exchangers into which the units are inserted
- Figures 15 to 17 illustrate alternative embodiments of the heat exchanger which may be constructed according to the present invention
- four plates 321 shaped as symmetric trapezoids are overlapped as shown and triangular-shaped corner portions 324 have a continuous outer wall 326 which can conduct heat to the finned section comprising alternating metal plate 321 /air gaps 328 where the heat is dissipated
- Four surfaces 326 may be used to dissipate heat from heat sources adjacent to each surface
- Figure 16 illustrates the same principle but using three plates 330 instead of four
- the structure of Figure 17 provides a heat transfer surface 326 produced by overlapping metal plates 340 to form two triangular shaped sections 342 comprising alternating plates in contact with each other
- FIGs 18 to 21 illustrate another embodiment of a heat exchanger constructed in accordance with the present invention
- a single plate 390 is provided with cut-out sections 392 and 394 From Figure 19 it can be seen that plate 390 includes an inclined lip 396 in the cut-out section 394 on opposed edges.
- Holes 392 define fan receptacles while lips 396 and cut-out portions 394 define a central cooling chamber into which a cooling module is inserted (not shown).
- the geometry of lips 396 and the tapered module provides good heat transfer to the air gaps 398 located between adjacent plates spaced from lips 336.
- Lips 336 are machined to provide a smooth uniform tapered surface.
- Dimples 391 are located on the bottom side of plate 390 which act as spacers in the stack.
- the solid portion is defined by the narrow overlapped lips 396.
- the substantial improvement in heat dissipation achieved with the heat exchangers disclosed herein is obtained by the combination of a solid surface (to which good thermal contact is made by the heat producing object) which extends into a finned heat dissipation area.
- the number of solid sections in any one heat exchanger may be tailored to accommodate any number of objects from which heat dissipation is desired.
- the configuration in Figure 16 may be used to cool three objects, the arrangement in Figure 15 may be used to cool four objects making thermal contact at positions 326.
- the preferred embodiments disclosed herein utilize aluminum plates provided with dimples extending transversely in both directions from the plane of the plate.
- Stacking the plates provides a solid central section with a finned section having air gaps between the plates except at the locations where the plates contact the dimples of the adjacent plates.
- a solid block could be machined to provide both a solid portion and the finned section as an alternative to use of multiple plates disclosed herein.
- FIG. 22 Another embodiment of a cooling device is shown in Figures 22 to 24.
- a heating and cooling device constructed in accordance with the present invention is shown at 300.
- Apparatus 300 is a table top plug-in unit which operates with between 50 to 200 watts input power and provides a larger surface area pad 302 having a heated section 304 adjacent to a cooled section 306.
- a power supply 308 provides power through electrical leads 315 to a thermoelectric unit 310 located between two identical water pumps 312 and 314 Pump 312 through which the heated water flows is in flow communication with a heat exchanger 316 provided with a fan 318 for dissipating excess heat.
- Power supply 308 provides power to fan 318 through leads 319. Water is supplied to the hot and cold sides from a water tank 320 and a microprocessor (not shown) may be integrated into the system for temperature control.
- FIGS 23 and 24 show in greater detail the hot side of the water pump system comprising pump 312 having a motor housing 336, and a housing 338 attached to motor housing 336.
- Housing 338 defines a first chamber 340 and an impeller enclosure 342.
- Chamber 340 is separated from impeller enclosure 342 by a disc 344 having a central aperture 346 to provide a fluid flow pathway between chamber 340 and impeller enclosure 342
- Housing 338 has an open end portion 343 ( Figure 24) into enclosure 342 and thermoelectric unit 310 is attached to housing 338 at open end portion 343.
- Side 326 of thermoelectric unit 310 is cooled and side 328 is heated when the current is switched on
- Pump 312 includes an impeller 348 mounted for rotation on a motor shaft 350 which passes through a seal 352 into housing 338 where it is connected to the motor.
- Impeller 348 is spaced from surface 328 of the thermoelectric unit by about 1 mm, best seen in Figure 23.
- An O- ⁇ ng 354 between thermoelectric unit 310 and housing 338 provides a water seal
- the fluid flow system includes a large water inlet tube 358 to introduce water from tank 320 into first chamber 340 in housing 338 This inlet allows for cross-flow exchange of liquid and air but does not provide recirculation
- an air escape passageway 360 extending from enclosure 342 to the inte ⁇ or of tube 358 is provided for exhausting trapped air or allowing air to vent out of the pump 312 thereby permitting the system to automatically prime and provide a static pressure on the system
- Passageways 364 extend through the side walls of housing 338 which provide fluid flow communication between first chamber 340 and tubes 366 and 382 shown in Figure 24.
- passageways 370 seen in Figure 23 extend through the side walls of housing 338 to provide fluid flow communication between impeller enclosure 342 and water outlet tubes 372 and 378 most visible in Figure 24
- water inlet tubes 358 extend up through the bottom of tank 320 and each has an end portion 322 which is spaced above the water level Tubes 358 are provided with holes 324 just above the bottom of tank 320, more clearly visible in Figure 23
- This water flow system comprising inlet tube 358, chamber 340, enclosure 342, air exhaust 360 and recirculation tubes 366, 372, 378 and 382 provides for cross-flow exchange of liquid and air but does not provide for recirculation between tank 320 and the pumps
- thermoelectric unit 310 When device 300 is assembled as shown in Figure 22, pump 314 is attached adjacent to side 326 of thermoelectric unit 310 and the pump is essentially identical to pump 312 just described above and water circulated over surface 326 of the thermoelect ⁇ c unit is cooled except when the water does not pass through heat exchanger 316 Tubes 378 and 382 on one side of pump 312 conduct heated water to heat exchanger 316 while for the cooled side with pump 314 the corresponding recirculation tubes (not shown) would not be used Tubes
- thermoelectric unit 310 The configuration of pumps 312 and 314 each with impeller 348 located adjacent to opposite sides of thermoelectric unit 310 is very advantageous in that it provides significantly more efficient heat transfer between the thermoelectric unit and the water compared to previous designs in which the pump is spaced away from the water heater and/or water cooler Rotating impeller 348 right adjacent to the surface of thermoelectric module 310 provides enhanced heat transfer (fluid shear against the heated/cooled surface) into the fluid thereby increasing the efficiency and cooling power over prior art devices The centrifugal effect created by the rotation of the impeller acts to create a pressure differential to give a pumping action useful for mixing the heat transfer liquid and for pumping the fluid through the systems to the components being cooled and heated. Using a single thermoelectric unit 310 to both heat and cool the water with pumps
- thermoelectric unit 310 is a Melcor CP 1 4-127-045L or similar device rated at 120 Watts with 15 Volts and 8 amps and a DC motor used to drive impeller 348 operates at 15 Volts below one ampere
- the water heating and cooling may be provided within safe physiological limits without the need for sophisticated and costly temperature and feedback control systems
- Flexible pad 302 may be secured to any part of the body using tape, VELCROTM straps and the like and may be readily deformed to fit the contours of the body
- Apparatus 300 may be modified so that the hot and cold sections 304 and 306 of water bag 302 are periodically switched to provide temporal temperature modulation in addition to spatial temperature modulation This may be done for example by connecting a heat exchanger and fan to pump 314 so that the hot and cold sides of the apparatus are mirror images of each other. Then the hot and cold sides may be rapidly switched by means of a four way ball valve used to redirect and interchange the hot and cold fluid paths.
- FIG. 25 to 29 illustrate an alternative embodiment of a cooling module 400 which may be used in the hot/cold therapy device of Figure 22.
- Module 400 includes a housing 402 comprising two matching sections 404 and 406 with section 404 provided with fluid flow passageways 410 and 412 and section 406 provided with passageways 414 and 416.
- a spigot 418 is attached to the housing at one end of channel 410 and a spigot 424 is attached at the other end. Similar spigots are located at the ends of channel 414.
- Each section 404 and 406 is provided with an inner O-ring groove 422 each to receive therein a separate O-ring 420 and each housing section defines an inner surface 408 sealed by the O-rings when the unit is assembled as in Figure 26a.
- Sandwiched between sections 404 and 406 is a thermoelectric unit 426 having two opposed surfaces 428 and 430 wherein one is heated and the other cooled when a voltage is applied across the unit. When the cooling unit is assembled together with the thermoelectric unit 426, a gap 432 exists between inner surfaces 408 and the opposing surface of the thermoelectric unit.
- Pump motors 436 are each provided with an impeller housing 438 housing an impeller (not shown) and the impeller housing of two pumps are inserted into channels 412 and 416 and sealed by O-rings 442, best seen in Figure 25.
- Each pump 436 has an outlet spigot 440 to which a water hose is connected which connects the unit to the cooling/heating blanket and/or a heat exchanger (not shown).
- fluid returns from the patient blanket (not shown) into spigot 418 through hose 460. Air bubbles are separated and return to the fluid reservoir (not shown) through spigot 424 and air return line 450 attached to the spigot ( Figure 28). Fluid is drawn across the surface 428 of the module 426. The gap 432 between housing surface 408 and module surface
- Fluid returning from the blanket through hose 460 into spigot 418 is allowed to fill reservoir 410 with sufficient fluid so as to provide a uniform flow across the entire cooled surface 428 (Figure 26c) of thermoelectric Peltier unit 426 to maximize cooling of the fluid
- the fluid contacts surface 428 at entry gap 411 and is drawn across the surface 428 and exits through exit gap 413 into reservoir or channel 412, see Figures 26a and 29 In this way the refrigerant is vigorously flowed across the cooled surface
- cooling module of Figure 5 achieves this by the impeller 164 being spaced from cooled surface 150 of thermoelectric unit 148 on the inside of chamber 112 with refrigerant being circulated across the chamber and up into impeller housing 162 and out through exit port 166
- the cooling module of Figure 24 achieves vigorous flow across surface 328 of thermoelectric unit 326 by rotating in a plane parallel surface 328 a short distance away from the surface
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Vascular Medicine (AREA)
- Thermal Sciences (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Physics & Mathematics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Mechanical Engineering (AREA)
- General Engineering & Computer Science (AREA)
- Thermotherapy And Cooling Therapy Devices (AREA)
Abstract
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU20200/97A AU2020097A (en) | 1996-04-01 | 1997-03-27 | Cold therapy device |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US1445196P | 1996-04-01 | 1996-04-01 | |
US60/014,451 | 1996-04-01 | ||
US08/803,939 | 1997-02-20 | ||
US08/803,939 US5895418A (en) | 1994-09-30 | 1997-02-20 | Device for producing cold therapy |
Publications (1)
Publication Number | Publication Date |
---|---|
WO1997036560A1 true WO1997036560A1 (fr) | 1997-10-09 |
Family
ID=26686120
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/CA1997/000198 WO1997036560A1 (fr) | 1996-04-01 | 1997-03-27 | Dispositif produisant du froid, pour usage therapeutique |
Country Status (3)
Country | Link |
---|---|
AU (1) | AU2020097A (fr) |
CA (1) | CA2201261C (fr) |
WO (1) | WO1997036560A1 (fr) |
Cited By (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2246919C2 (ru) * | 2002-11-22 | 2005-02-27 | Дагестанский государственный технический университет | Устройство для пульсирующего теплового воздействия на назолабиальную область, адаптивное к ритму дыхания пациента |
GB2437710A (en) * | 2006-05-03 | 2007-11-07 | Richard Frank Guttfield | Bed cooling accessory |
US7454959B2 (en) | 2003-12-23 | 2008-11-25 | Dionex Softron Gmbh | Method and device for providing defined fluid flow, especially for use in liquid chromatography |
US8236038B2 (en) | 2006-04-20 | 2012-08-07 | University Of Pittsburgh-Of The Commonwealth System Of Higher Education | Method and apparatus of noninvasive, regional brain thermal stimuli for the treatment of neurological disorders |
US8425583B2 (en) | 2006-04-20 | 2013-04-23 | University of Pittsburgh—of the Commonwealth System of Higher Education | Methods, devices and systems for treating insomnia by inducing frontal cerebral hypothermia |
US9211212B2 (en) | 2006-04-20 | 2015-12-15 | Cerêve, Inc. | Apparatus and method for modulating sleep |
US9492313B2 (en) | 2006-04-20 | 2016-11-15 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Method and apparatus of noninvasive, regional brain thermal stimuli for the treatment of neurological disorders |
EP3192477A1 (fr) * | 2016-01-14 | 2017-07-19 | Hilotherm Holding AG | Appareil médical de régulation de température |
US10058674B2 (en) | 2013-01-02 | 2018-08-28 | Ebb Therapeutics, Inc. | Systems for enhancing sleep |
US11684510B2 (en) | 2006-04-20 | 2023-06-27 | University of Pittsburgh—of the Commonwealth System of Higher Education | Noninvasive, regional brain thermal stimuli for the treatment of neurological disorders |
CN117084910B (zh) * | 2023-10-20 | 2023-12-29 | 厦门维优智能科技有限公司 | 一种冷热敷温度可调的空气波治疗仪 |
EP4338716A1 (fr) * | 2022-09-15 | 2024-03-20 | Shenzhen Youbosi Technology Co., Ltd. | Dispositif de commande pour système double froid et chaud |
US12290640B2 (en) | 2006-04-20 | 2025-05-06 | University of Pittsburgh—of the Commonwealth System of Higher Education | Noninvasive, regional brain thermal stimulation for inducing relaxation |
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FR2579888A1 (en) * | 1985-04-05 | 1986-10-10 | Charton Michel | Method and apparatus for regulating the temperature of a coolant fluid to a predetermined temperature level, and utilisation of this method or of the apparatus for producing medical hypo/hyperthermia |
US4741338A (en) * | 1986-10-06 | 1988-05-03 | Toshiaki Miyamae | Thermoelectric physical remedy apparatus |
EP0342676A2 (fr) * | 1988-05-20 | 1989-11-23 | Temperature Research Corporation | Appareil pour le traitement local de chaleur et de froid |
US5097829A (en) * | 1990-03-19 | 1992-03-24 | Tony Quisenberry | Temperature controlled cooling system |
-
1997
- 1997-03-27 AU AU20200/97A patent/AU2020097A/en not_active Abandoned
- 1997-03-27 CA CA 2201261 patent/CA2201261C/fr not_active Expired - Lifetime
- 1997-03-27 WO PCT/CA1997/000198 patent/WO1997036560A1/fr active Application Filing
Patent Citations (4)
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FR2579888A1 (en) * | 1985-04-05 | 1986-10-10 | Charton Michel | Method and apparatus for regulating the temperature of a coolant fluid to a predetermined temperature level, and utilisation of this method or of the apparatus for producing medical hypo/hyperthermia |
US4741338A (en) * | 1986-10-06 | 1988-05-03 | Toshiaki Miyamae | Thermoelectric physical remedy apparatus |
EP0342676A2 (fr) * | 1988-05-20 | 1989-11-23 | Temperature Research Corporation | Appareil pour le traitement local de chaleur et de froid |
US5097829A (en) * | 1990-03-19 | 1992-03-24 | Tony Quisenberry | Temperature controlled cooling system |
Cited By (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2246919C2 (ru) * | 2002-11-22 | 2005-02-27 | Дагестанский государственный технический университет | Устройство для пульсирующего теплового воздействия на назолабиальную область, адаптивное к ритму дыхания пациента |
US7454959B2 (en) | 2003-12-23 | 2008-11-25 | Dionex Softron Gmbh | Method and device for providing defined fluid flow, especially for use in liquid chromatography |
US9669185B2 (en) | 2006-04-20 | 2017-06-06 | University of Pittsburgh—of the Commonwealth System of Higher Education | Methods, devices and systems for treating insomnia by inducing frontal cerebral hypothermia |
US10610661B2 (en) | 2006-04-20 | 2020-04-07 | University of Pittsburgh—of the Commonwealth System of Higher Education | Noninvasive, regional brain thermal stimuli for the treatment of migraine |
US8425583B2 (en) | 2006-04-20 | 2013-04-23 | University of Pittsburgh—of the Commonwealth System of Higher Education | Methods, devices and systems for treating insomnia by inducing frontal cerebral hypothermia |
US9089400B2 (en) | 2006-04-20 | 2015-07-28 | University of Pittsburgh—of the Commonwealth System of Higher Education | Methods, devices and systems for treating insomnia by inducing frontal cerebral hypothermia |
US9211212B2 (en) | 2006-04-20 | 2015-12-15 | Cerêve, Inc. | Apparatus and method for modulating sleep |
US9492313B2 (en) | 2006-04-20 | 2016-11-15 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Method and apparatus of noninvasive, regional brain thermal stimuli for the treatment of neurological disorders |
US12290640B2 (en) | 2006-04-20 | 2025-05-06 | University of Pittsburgh—of the Commonwealth System of Higher Education | Noninvasive, regional brain thermal stimulation for inducing relaxation |
US11684510B2 (en) | 2006-04-20 | 2023-06-27 | University of Pittsburgh—of the Commonwealth System of Higher Education | Noninvasive, regional brain thermal stimuli for the treatment of neurological disorders |
US8236038B2 (en) | 2006-04-20 | 2012-08-07 | University Of Pittsburgh-Of The Commonwealth System Of Higher Education | Method and apparatus of noninvasive, regional brain thermal stimuli for the treatment of neurological disorders |
US10213334B2 (en) | 2006-04-20 | 2019-02-26 | Ebb Therapeutics, Inc. | Apparatus and method for modulating sleep |
GB2437710A (en) * | 2006-05-03 | 2007-11-07 | Richard Frank Guttfield | Bed cooling accessory |
US10058674B2 (en) | 2013-01-02 | 2018-08-28 | Ebb Therapeutics, Inc. | Systems for enhancing sleep |
US10864348B2 (en) | 2013-01-02 | 2020-12-15 | Ebb Therapeutics, Inc. | Systems for enhancing sleep |
EP3192477A1 (fr) * | 2016-01-14 | 2017-07-19 | Hilotherm Holding AG | Appareil médical de régulation de température |
EP4338716A1 (fr) * | 2022-09-15 | 2024-03-20 | Shenzhen Youbosi Technology Co., Ltd. | Dispositif de commande pour système double froid et chaud |
CN117084910B (zh) * | 2023-10-20 | 2023-12-29 | 厦门维优智能科技有限公司 | 一种冷热敷温度可调的空气波治疗仪 |
Also Published As
Publication number | Publication date |
---|---|
AU2020097A (en) | 1997-10-22 |
CA2201261C (fr) | 2006-06-20 |
CA2201261A1 (fr) | 1997-10-01 |
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