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WO2001083010A1 - Distributeur de produits antimicrobiens - Google Patents

Distributeur de produits antimicrobiens Download PDF

Info

Publication number
WO2001083010A1
WO2001083010A1 PCT/CA2001/000626 CA0100626W WO0183010A1 WO 2001083010 A1 WO2001083010 A1 WO 2001083010A1 CA 0100626 W CA0100626 W CA 0100626W WO 0183010 A1 WO0183010 A1 WO 0183010A1
Authority
WO
WIPO (PCT)
Prior art keywords
liquid
improvement
metallo
dispensing
releasing agent
Prior art date
Application number
PCT/CA2001/000626
Other languages
English (en)
Inventor
Garth T. Webb
Original Assignee
Webb Garth T
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Webb Garth T filed Critical Webb Garth T
Priority to AU2001254577A priority Critical patent/AU2001254577A1/en
Publication of WO2001083010A1 publication Critical patent/WO2001083010A1/fr

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B11/00—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
    • B05B11/0005—Components or details
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/1443—Containers with means for dispensing liquid medicaments in a filtered or sterile way, e.g. with bacterial filters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/16—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using chemical substances
    • A61L2/23—Solid substances, e.g. granules, powders, blocks, tablets
    • A61L2/238—Metals or alloys, e.g. oligodynamic metals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/006—Sprayers or atomisers specially adapted for therapeutic purposes operated by applying mechanical pressure to the liquid to be sprayed or atomised
    • A61M11/008—Sprayers or atomisers specially adapted for therapeutic purposes operated by applying mechanical pressure to the liquid to be sprayed or atomised by squeezing, e.g. using a flexible bottle or a bulb
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/06—Sprayers or atomisers specially adapted for therapeutic purposes of the injector type
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/165—Filtering accessories, e.g. blood filters, filters for infusion liquids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B11/00—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
    • B05B11/0005—Components or details
    • B05B11/0062—Outlet valves actuated by the pressure of the fluid to be sprayed
    • B05B11/0064—Lift valves
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B11/00—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
    • B05B11/0005—Components or details
    • B05B11/0062—Outlet valves actuated by the pressure of the fluid to be sprayed
    • B05B11/007—Outlet valves actuated by the pressure of the fluid to be sprayed being opened by deformation of a sealing element made of resiliently deformable material, e.g. flaps, skirts, duck-bill valves
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D83/00—Containers or packages with special means for dispensing contents
    • B65D83/14—Containers for dispensing liquid or semi-liquid contents by internal gaseous pressure, i.e. aerosol containers comprising propellant
    • B65D83/75—Aerosol containers not provided for in groups B65D83/16 - B65D83/74
    • B65D83/753—Aerosol containers not provided for in groups B65D83/16 - B65D83/74 characterised by details or accessories associated with outlets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/1468—Containers characterised by specific material properties
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/0043—Catheters; Hollow probes characterised by structural features
    • A61M2025/0056—Catheters; Hollow probes characterised by structural features provided with an antibacterial agent, e.g. by coating, residing in the polymer matrix or releasing an agent out of a reservoir
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/75—General characteristics of the apparatus with filters

Definitions

  • the invention relates to the field of liquid dispensers, particularly dispensers for dispensing sterile liquids such as medications.
  • Medicaments such as asthma medication are often dispensed by aerosol spray or atomizers.
  • various liquids require sterile dispensing. Insulin, for example, must be dispensed in sterile form.
  • a container holds the liquid to be dispensed and a dispensing head is provided on the container which has a dispensing channel connecting the interior of the container to the exterior air.
  • a pump of some kind is provided to allow the user to dispense the liquid.
  • the upper region of the container must be kept at atmospheric pressure for the dispensing action to work, which means there will be communication between the exterior atmosphere and the interior of the container, so that air uptake by the container can occur, giving rise to contamination of the liquid in the interior of the container.
  • the present applicant's international application PCT/CA99/01002 published May 4, 2000 discloses a device for dispensing a vaporized spray of sterile medicated liquid, comprising a housing for containing a supply of sterile medicated liquid, means for pressurizing the liquid, and a combination atomizing and pressure release valve.
  • the combination atomizing and pressure release valve comprises a layer of flexible material provided with an aperture, and a plug extending upwardly through the aperture and having a surface against which the layer of flexible material is biassed in the closed position, the layer lifting off the surface of the plug in the open position to thereby open the aperture.
  • 5,492,252 provides for a flap valve to reduce contamination to liquid trapped within the dispensing channel. While such a flap valve may reduce exposure of the liquid within the dispensing channel, it does little to reduce microbial contamination around the spout and flap valve itself. Microbial contamination would spread to the dispensing channel from the spout and flap valve. There is therefore a need for both a physical and a chemical barrier to micro-organisms in dispensers for sterile liquids.
  • the object of the present invention is to simultaneously provide both a physical and chemical barrier against microbial contamination in multi-purpose liquid dispensing devices.
  • the present invention provides a liquid-dispensing device in which the dispensed liquid is forced through a pressure release valve and in the course of doing so is brought into contact with a metallo- releasing agent.
  • a metallo-releasing agent is selected from the group of boron, chromium, manganese, iron, cobalt, nickel, copper, zinc, rhodium, palladium, silver, tin, platinum and gold, and mixture and alloys of the foregoing.
  • Fig. 1 is a cross-sectional view of a first embodiment of the invention
  • Fig. 2 is a cross-sectional view of a second embodiment of the invention.
  • Fig. 3 is a cross-sectional view of the embodiment of the invention shown in Fig. 2 with a removable cap. Best Modefs) For Carrying Out the Invention
  • a liquid dispensing device 8 has a liquid dispensing channel 10 formed in the neck 12 of the dispenser 8, and communicates with the interior of the liquid-containing portion of the dispenser or a pump mechanism (not shown).
  • a valve seat 14 is formed in the neck 12 and seats a ball valve 16 which is biased in a closed position by spring 18.
  • the dispensing channel 10 extends through, at its end, a dispensing tube or spout 20 which is preferably lined on its interior surface 21 with silver.
  • a removable cap 22 is provided which has a conical silver lid 24 which is forced into the end of, and in contact with, dispensing tube 20 when cap 22 is in place.
  • the dispensed liquid is forced into the dispensing channel 10 by squeezing the collapsible container, or actuating the pumping mechanism attached to the container. Pressure may alternately be supplied to the liquid by a source of compressed air attached to the liquid dispenser. The pressure of the liquid forces ball valve 16 off its seat and the liquid flows out the dispensing tube. When the pressure is removed, the ball valve 16 returns to its seat 14 and closes dispensing channel 10. Any liquid remaining on the interior of dispensing tube 20 is in contact with the silver lining 21. It is known that ions from the silver metal go into solution with the liquid, or alternately form hydrogen peroxide on the surface of the metal, to form an anti-microbial solution which is non-toxic in mild solution. When the cap is replaced, silver lid 24 forms another anti-microbial surface in contact with any liquid remaining in tube 20, so that any surplus liquid remaining in or adjacent tube 20 is maintained sterile while the device is not in use.
  • Fig. 2 illustrates an alternate embodiment in which the spout consists of hole 30 in a flexible (e.g. rubber) diaphragm 32.
  • the edge 34 of the diaphragm is secured by an insert 34 in neck 36.
  • diaphragm 32 is stretched across, and bears tightly against, silver ball 38 which is fixed in seat 40 on valve support 41.
  • Valve support 41 has a circular channel 42 through which liquid under pressure flows around ball 38 and out spout 30.
  • the dispensed liquid is forced into the dispensing channel 42 by squeezing the collapsible container, or actuating the pumping mechanism attached to the container as above.
  • the pressure of the liquid forces diaphragm 32 off ball 38 and the liquid flows out the spout 30.
  • the diaphragm 32 returns to its position against ball 38, closing hole 30. Any liquid remaining in the interior of the valve adjacent ball 38 is in contact with the silver surface of ball 38 and remains sterile due to the anti-microbial effect of the silver as described above.
  • the interior surface 33 of the diaphragm may be coated with the metallo-releasing agent instead of or in addition to having the agent on the surface of ball 38.
  • Fig. 3 illustrates a removable cap 50 for the embodiment of the invention shown in Fig. 2.
  • a silver coated lid 52 Secured to its lower surface 51 is a silver coated lid 52 which has a concave lower surface 53 to fit over, and contact the edges of hole 30 when the cap 50 is in place, thereby maintaining sterile any liquid left in that area.
  • metallo-releasing agents also work in substitution for silver. These include boron, chromium, manganese, iron, cobalt, nickel, copper, zinc, rhodium, palladium, tin, platinum, gold as well as silver, and mixtures of these, and alloys of these elements.

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Anesthesiology (AREA)
  • Mechanical Engineering (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Vascular Medicine (AREA)
  • Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
  • Closures For Containers (AREA)

Abstract

Selon l'invention, dans les distributeurs précédents, le liquide restant dans le bec verseur en contact avec l'atmosphère peut être contaminé et contaminer le liquide distribué ultérieurement. La présente invention concerne un dispositif (8) distributeur de liquides où l'on force le liquide distribué à traverser une soupape (16) de décompression, l'amenant ainsi en contact avec un agent de libération de métal. Cet agent de libération est choisi de préférence dans le groupe constitué par le bore, le chrome, le manganèse, le fer, le cobalt, le nickel, le cuivre, le zinc, le rhodium, le palladium, l'argent, l'étain, le platine et l'or, ainsi que par leurs mélanges et alliages.
PCT/CA2001/000626 2000-05-03 2001-04-30 Distributeur de produits antimicrobiens WO2001083010A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2001254577A AU2001254577A1 (en) 2000-05-03 2001-04-30 Anti-microbial dispenser

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CA2,307,478 2000-05-03
CA 2307478 CA2307478A1 (fr) 2000-05-03 2000-05-03 Distributeur antimicrobien

Publications (1)

Publication Number Publication Date
WO2001083010A1 true WO2001083010A1 (fr) 2001-11-08

Family

ID=4166072

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/CA2001/000626 WO2001083010A1 (fr) 2000-05-03 2001-04-30 Distributeur de produits antimicrobiens

Country Status (3)

Country Link
AU (1) AU2001254577A1 (fr)
CA (1) CA2307478A1 (fr)
WO (1) WO2001083010A1 (fr)

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1380351A1 (fr) * 2002-07-13 2004-01-14 AERO Pump GmbH, Zerstäuberpumpen Pompe distributrice avec dispositif antibactérienne
EP1466668A1 (fr) * 2003-04-09 2004-10-13 URSAPHARM Arzneimittel GmbH & Co. KG Distributeur de produit fluide
FR2951441A1 (fr) * 2009-10-20 2011-04-22 Valois Sas Tete de distribution pour dispositif de distribution de produit fluide.
DE102010045059A1 (de) * 2010-09-10 2012-03-15 F. Holzer Gmbh Dosiervorrichtung
DE102010048986A1 (de) * 2010-10-20 2012-04-26 Ursapharm Arzneimittel Gmbh Dosierpumpe
DE102010063592A1 (de) * 2010-12-20 2012-06-21 Ing. Erich Pfeiffer Gmbh Spender für Flüssigkeiten
DE102011086755A1 (de) * 2011-11-21 2013-05-23 Aptar Radolfzell Gmbh Spender zum Austrag von pharmazeutischen Flüssigkeiten
WO2013072635A1 (fr) * 2011-11-17 2013-05-23 Rexam Dispensing Systems Tête de distribution pour un système de distribution d'un produit sous pression
WO2014095004A1 (fr) * 2012-12-20 2014-06-26 Meadwestvaco Calmar Gmbh Distributeur muni d'un capuchon de protection contenant un insert antimicrobien
DE102017105246A1 (de) 2017-03-13 2018-09-13 Ursatec Verpackung Gmbh Fluidspender
WO2025094074A1 (fr) * 2023-10-30 2025-05-08 Merxin Limited Dispositif de distribution de liquide doté d'une valve unidirectionnelle

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3794247A (en) * 1972-11-22 1974-02-26 Corsette Douglas Frank Spray fitment for squeeze bottles
US4309992A (en) * 1980-07-11 1982-01-12 Dodak Michael J Microbicidal filter
US4418686A (en) * 1979-08-01 1983-12-06 Child Laboratories Inc. Implant for inhibiting mastitis in dairy cattle
US5234138A (en) * 1990-08-29 1993-08-10 L'oreal Self-closing dispenser for a container containing a liquid or pasty product
US5360145A (en) * 1992-07-21 1994-11-01 L'oreal Dispenser for at least one liquid or pasty product comprising a closure system that allows no ingress of air, and preservation process using the said dispenser
DE19542959C1 (de) * 1995-11-17 1996-10-24 Ursatec Verpackung Gmbh Vor Kontamination schützende Abgabevorrichtung für Fluide
US5614172A (en) * 1990-08-29 1997-03-25 Ursapharm Arzneimittel Gmbh Fluid dispenser for germ-free fluid
US5877243A (en) * 1997-05-05 1999-03-02 Icet, Inc. Encrustation and bacterial resistant coatings for medical applications

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3794247A (en) * 1972-11-22 1974-02-26 Corsette Douglas Frank Spray fitment for squeeze bottles
US4418686A (en) * 1979-08-01 1983-12-06 Child Laboratories Inc. Implant for inhibiting mastitis in dairy cattle
US4309992A (en) * 1980-07-11 1982-01-12 Dodak Michael J Microbicidal filter
US5234138A (en) * 1990-08-29 1993-08-10 L'oreal Self-closing dispenser for a container containing a liquid or pasty product
US5614172A (en) * 1990-08-29 1997-03-25 Ursapharm Arzneimittel Gmbh Fluid dispenser for germ-free fluid
US5360145A (en) * 1992-07-21 1994-11-01 L'oreal Dispenser for at least one liquid or pasty product comprising a closure system that allows no ingress of air, and preservation process using the said dispenser
DE19542959C1 (de) * 1995-11-17 1996-10-24 Ursatec Verpackung Gmbh Vor Kontamination schützende Abgabevorrichtung für Fluide
US5877243A (en) * 1997-05-05 1999-03-02 Icet, Inc. Encrustation and bacterial resistant coatings for medical applications

Cited By (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1380351A1 (fr) * 2002-07-13 2004-01-14 AERO Pump GmbH, Zerstäuberpumpen Pompe distributrice avec dispositif antibactérienne
US6851583B2 (en) 2002-07-13 2005-02-08 Aero Pump Gmbh Double-acting pump for ejecting a product from a container
EP1466668A1 (fr) * 2003-04-09 2004-10-13 URSAPHARM Arzneimittel GmbH & Co. KG Distributeur de produit fluide
FR2951441A1 (fr) * 2009-10-20 2011-04-22 Valois Sas Tete de distribution pour dispositif de distribution de produit fluide.
WO2011048332A1 (fr) * 2009-10-20 2011-04-28 Valois Sas Tete de distribution pour dispositif de distribution de produit fluide.
DE102010045059A1 (de) * 2010-09-10 2012-03-15 F. Holzer Gmbh Dosiervorrichtung
US9415925B2 (en) 2010-09-10 2016-08-16 F. Holzer Gmbh Metering device
DE102010048986A1 (de) * 2010-10-20 2012-04-26 Ursapharm Arzneimittel Gmbh Dosierpumpe
WO2012084557A1 (fr) * 2010-12-20 2012-06-28 Ing. Erich Pfeiffer Gmbh Distributeur de liquides
DE102010063592A1 (de) * 2010-12-20 2012-06-21 Ing. Erich Pfeiffer Gmbh Spender für Flüssigkeiten
WO2013072635A1 (fr) * 2011-11-17 2013-05-23 Rexam Dispensing Systems Tête de distribution pour un système de distribution d'un produit sous pression
FR2982850A1 (fr) * 2011-11-17 2013-05-24 Rexam Dispensing Sys Tete de distribution pour un systeme de distribution d'un produit sous pression
CN103987465A (zh) * 2011-11-17 2014-08-13 阿拉贝阿勒特雷波尔简易股份公司 用于加压产品分配系统的分配头
DE102011086755A1 (de) * 2011-11-21 2013-05-23 Aptar Radolfzell Gmbh Spender zum Austrag von pharmazeutischen Flüssigkeiten
US9833356B2 (en) 2011-11-21 2017-12-05 Aptar Radolfzell Gmbh Dispenser for dispensing pharmaceutical liquids
WO2014095004A1 (fr) * 2012-12-20 2014-06-26 Meadwestvaco Calmar Gmbh Distributeur muni d'un capuchon de protection contenant un insert antimicrobien
US9714132B2 (en) 2012-12-20 2017-07-25 WestRock Dispensing Systems Hemer GmbH Manually operated dispenser for media
DE102017105246A1 (de) 2017-03-13 2018-09-13 Ursatec Verpackung Gmbh Fluidspender
WO2025094074A1 (fr) * 2023-10-30 2025-05-08 Merxin Limited Dispositif de distribution de liquide doté d'une valve unidirectionnelle

Also Published As

Publication number Publication date
AU2001254577A1 (en) 2001-11-12
CA2307478A1 (fr) 2001-11-03

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