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WO2008139124A3 - Preparations pharmaceutiques ou cosmetiques pour application topique et/ou parenterale, leurs procedes de preparation, et leurs utilisations - Google Patents

Preparations pharmaceutiques ou cosmetiques pour application topique et/ou parenterale, leurs procedes de preparation, et leurs utilisations Download PDF

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Publication number
WO2008139124A3
WO2008139124A3 PCT/FR2008/050726 FR2008050726W WO2008139124A3 WO 2008139124 A3 WO2008139124 A3 WO 2008139124A3 FR 2008050726 W FR2008050726 W FR 2008050726W WO 2008139124 A3 WO2008139124 A3 WO 2008139124A3
Authority
WO
WIPO (PCT)
Prior art keywords
topical
pharmaceutical
parenteral application
same
preparation methods
Prior art date
Application number
PCT/FR2008/050726
Other languages
English (en)
Other versions
WO2008139124A2 (fr
Inventor
Marc Moutet
Jean-Claude Yadan
Original Assignee
Galderma Res & Dev
Marc Moutet
Jean-Claude Yadan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Galderma Res & Dev, Marc Moutet, Jean-Claude Yadan filed Critical Galderma Res & Dev
Priority to CA002686511A priority Critical patent/CA2686511A1/fr
Priority to EP08788214A priority patent/EP2155186A2/fr
Priority to US12/599,645 priority patent/US20100298249A1/en
Publication of WO2008139124A2 publication Critical patent/WO2008139124A2/fr
Publication of WO2008139124A3 publication Critical patent/WO2008139124A3/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/60—Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/07—Retinol compounds, e.g. vitamin A
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/203—Retinoic acids ; Salts thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7016—Disaccharides, e.g. lactose, lactulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34—Alcohols
    • A61K8/347—Phenols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/36—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/63—Steroids; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67—Vitamins
    • A61K8/671—Vitamin A; Derivatives thereof, e.g. ester of vitamin A acid, ester of retinol, retinol, retinal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/08—Anti-ageing preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/52—Stabilizers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/91—Injection

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Birds (AREA)
  • Emergency Medicine (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Molecular Biology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

L' invention concerne une composition pharmaceutique ou cosmétique pour application topique et/ou parentérale comprenant, dans un milieu physiologiquement acceptable, au moins un rétinoïde ou ses sels et dérivés, et au moins un inhibiteur de la dégradation de l'acide hyaluronique. L'invention s'applique en particulier en dermatologie humaine ou en chirurgie réparatrice.
PCT/FR2008/050726 2007-05-11 2008-04-22 Preparations pharmaceutiques ou cosmetiques pour application topique et/ou parenterale, leurs procedes de preparation, et leurs utilisations WO2008139124A2 (fr)

Priority Applications (3)

Application Number Priority Date Filing Date Title
CA002686511A CA2686511A1 (fr) 2007-05-11 2008-04-22 Preparations pharmaceutiques ou cosmetiques pour application topique et/ou parenterale, leurs procedes de preparation, et leurs utilisations
EP08788214A EP2155186A2 (fr) 2007-05-11 2008-04-22 Preparations pharmaceutiques ou cosmetiques pour application topique et/ou parenterale, leurs procedes de preparation, et leurs utilisations
US12/599,645 US20100298249A1 (en) 2007-05-11 2008-04-22 Pharmaceutical or cosmetic preparations for topical and/or parenteral application, preparation methods thereof and use of same

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0755026 2007-05-11
FR0755026 2007-05-11

Publications (2)

Publication Number Publication Date
WO2008139124A2 WO2008139124A2 (fr) 2008-11-20
WO2008139124A3 true WO2008139124A3 (fr) 2009-02-05

Family

ID=38786904

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/FR2008/050726 WO2008139124A2 (fr) 2007-05-11 2008-04-22 Preparations pharmaceutiques ou cosmetiques pour application topique et/ou parenterale, leurs procedes de preparation, et leurs utilisations

Country Status (4)

Country Link
US (1) US20100298249A1 (fr)
EP (1) EP2155186A2 (fr)
CA (1) CA2686511A1 (fr)
WO (1) WO2008139124A2 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG10202008097VA (en) * 2010-12-23 2020-09-29 Amazentis Sa Compositions and methods for improving mitochondrial function and treating neurodegenerative diseases and cognitive disorders
CN105142632B (zh) * 2012-06-27 2020-01-07 阿马曾提斯公司 通过投予尿石素或其前体增强自噬或增加寿命

Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5723139A (en) * 1996-09-27 1998-03-03 Chesebrough-Pond's Usa Co., Division Of Conopco, Inc. Skin care compositions containing a polycyclic triterpene carboxylic acid and a retinoid
DE19806946A1 (de) * 1998-02-19 1999-09-09 Beiersdorf Ag Kosmetische oder dermatologische Wirkstoffkombinationen aus mindestens einer Substanz gewählt aus der Gruppe, bestehend aus Carnitin und den Acylcarnitinen, und mindestens einem Retinoid sowie Zubereitungen mit einem Gehalt an solchen Wirkstoffkombinationen
US6024941A (en) * 1992-07-13 2000-02-15 Shiseido Company, Ltd. External skin treatment composition
EP1023897A2 (fr) * 1999-01-26 2000-08-02 Showa Denko Kabushiki Kaisha Agent dermatologique
KR20010001290A (ko) * 1999-06-03 2001-01-05 서경배 피부 주름의 개선 및 생성 억제 효과를 갖는 외용제 조성물
WO2001085129A2 (fr) * 2000-05-05 2001-11-15 Johnson & Johnson Consumer Companies, Inc. Composition pour le soin de la peau
WO2002002074A2 (fr) * 2000-06-30 2002-01-10 Unilever Plc Compositions pour le soin de la peau renfermant des composes qui reproduisent l'effet de l'acide retinoique sur la peau
WO2004000242A1 (fr) * 2002-06-25 2003-12-31 Cosmeceutic Solutions Pty Ltd Compositions cosmetiques topiques
EP1514536A1 (fr) * 2003-09-10 2005-03-16 JOHNSON & JOHNSON CONSUMER COMPANIES, INC. Compositions Topiques
WO2007074288A1 (fr) * 2005-12-21 2007-07-05 Galderma Research & Development Preparations pharmaceutiques ou cosmetiques pour application topique et/ou parenterale, leurs procedes de preparation, et leurs utilisations

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US523139A (en) * 1894-07-17 Thread-package
US4439614A (en) * 1982-09-22 1984-03-27 Sri International 5,6-Methano-5,6-dihydroretinoids
US4879114A (en) * 1985-12-20 1989-11-07 Angio-Medical Corporation Lipids from omentum and methods for cosmetic use
US6008254A (en) * 1997-05-09 1999-12-28 Kligman; Douglas E. Method of treating skin disorders with high-strength tretinoin
US6689349B1 (en) * 1998-12-23 2004-02-10 Esparma Gmbh Skin protection agents containing a fragment mixture produced from hyaluronic acid by hydrolysis
ITMI20020756A1 (it) * 2002-04-09 2003-10-09 Sinclair Pharma S R L Composizioni farmaceutiche topiche per il trattamento delle dermatiti

Patent Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6024941A (en) * 1992-07-13 2000-02-15 Shiseido Company, Ltd. External skin treatment composition
US5723139A (en) * 1996-09-27 1998-03-03 Chesebrough-Pond's Usa Co., Division Of Conopco, Inc. Skin care compositions containing a polycyclic triterpene carboxylic acid and a retinoid
DE19806946A1 (de) * 1998-02-19 1999-09-09 Beiersdorf Ag Kosmetische oder dermatologische Wirkstoffkombinationen aus mindestens einer Substanz gewählt aus der Gruppe, bestehend aus Carnitin und den Acylcarnitinen, und mindestens einem Retinoid sowie Zubereitungen mit einem Gehalt an solchen Wirkstoffkombinationen
EP1023897A2 (fr) * 1999-01-26 2000-08-02 Showa Denko Kabushiki Kaisha Agent dermatologique
KR20010001290A (ko) * 1999-06-03 2001-01-05 서경배 피부 주름의 개선 및 생성 억제 효과를 갖는 외용제 조성물
WO2001085129A2 (fr) * 2000-05-05 2001-11-15 Johnson & Johnson Consumer Companies, Inc. Composition pour le soin de la peau
WO2002002074A2 (fr) * 2000-06-30 2002-01-10 Unilever Plc Compositions pour le soin de la peau renfermant des composes qui reproduisent l'effet de l'acide retinoique sur la peau
WO2004000242A1 (fr) * 2002-06-25 2003-12-31 Cosmeceutic Solutions Pty Ltd Compositions cosmetiques topiques
EP1514536A1 (fr) * 2003-09-10 2005-03-16 JOHNSON & JOHNSON CONSUMER COMPANIES, INC. Compositions Topiques
WO2007074288A1 (fr) * 2005-12-21 2007-07-05 Galderma Research & Development Preparations pharmaceutiques ou cosmetiques pour application topique et/ou parenterale, leurs procedes de preparation, et leurs utilisations

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
DATABASE WPI Week 200146, Derwent World Patents Index; AN 2001-430654, XP002463273 *
FURUYA T ET AL: "BIOCHEMICAL CHARACTERIZATION OF GLYCYRRHIZIN AS AN EFFECTIVE INHIBITOR FOR HYALURONIDASE FROM BOVINE TESTIS", BIOLOGICAL & PHARMACEUTICAL BULLETIN (OF JAPAN), PHARMACEUTICAL SOCIETY OF JAPAN, TOKYO, JP, vol. 20, no. 9, September 1997 (1997-09-01), pages 973 - 977, XP001207776, ISSN: 0918-6158 *
GIRISH ET AL: "The magic glue hyaluronan and its eraser hyaluronidase: A biological overview", LIFE SCIENCES, PERGAMON PRESS, OXFORD, GB, vol. 80, no. 21, 20 April 2007 (2007-04-20), pages 1921 - 1943, XP022036977, ISSN: 0024-3205 *

Also Published As

Publication number Publication date
WO2008139124A2 (fr) 2008-11-20
CA2686511A1 (fr) 2008-11-20
EP2155186A2 (fr) 2010-02-24
US20100298249A1 (en) 2010-11-25

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