[go: up one dir, main page]

WO2009031375A1 - 電気化学的センサ装置及びこれを用いた電気化学的測定方法 - Google Patents

電気化学的センサ装置及びこれを用いた電気化学的測定方法 Download PDF

Info

Publication number
WO2009031375A1
WO2009031375A1 PCT/JP2008/063667 JP2008063667W WO2009031375A1 WO 2009031375 A1 WO2009031375 A1 WO 2009031375A1 JP 2008063667 W JP2008063667 W JP 2008063667W WO 2009031375 A1 WO2009031375 A1 WO 2009031375A1
Authority
WO
WIPO (PCT)
Prior art keywords
sensor device
electrochemical
electrochemical sensor
same
measuring method
Prior art date
Application number
PCT/JP2008/063667
Other languages
English (en)
French (fr)
Inventor
Junji Fukuda
Hiroaki Suzuki
Kentaro Okamura
Masatoshi Hashimoto
Takahisa Anada
Hideki Kuramitsu
Go Tazaki
Original Assignee
University Of Tsukuba
Kuraray Co., Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University Of Tsukuba, Kuraray Co., Ltd. filed Critical University Of Tsukuba
Priority to US12/733,533 priority Critical patent/US8303800B2/en
Priority to JP2009531162A priority patent/JP5050251B2/ja
Publication of WO2009031375A1 publication Critical patent/WO2009031375A1/ja

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/27—Association of two or more measuring systems or cells, each measuring a different parameter, where the measurement results may be either used independently, the systems or cells being physically associated, or combined to produce a value for a further parameter
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0627—Sensor or part of a sensor is integrated
    • B01L2300/0645—Electrodes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0816—Cards, e.g. flat sample carriers usually with flow in two horizontal directions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0867—Multiple inlets and one sample wells, e.g. mixing, dilution
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/08—Regulating or influencing the flow resistance
    • B01L2400/084—Passive control of flow resistance
    • B01L2400/086—Passive control of flow resistance using baffles or other fixed flow obstructions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B33—ADDITIVE MANUFACTURING TECHNOLOGY
    • B33Y—ADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3-D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3-D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
    • B33Y80/00—Products made by additive manufacturing

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Clinical Laboratory Science (AREA)
  • Dispersion Chemistry (AREA)
  • Molecular Biology (AREA)
  • Electrochemistry (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)

Abstract

　測定感度を維持しつつ流路の微小化を図ることができ、微量の試料に含まれる対象物質を確実に定量できる電気化学的センサ装置を提供する。 　基板に形成された流路部（１０）と、流路部（１０）内を流通する溶液に含まれる対象物質を電気化学的に測定するための作用電極（２０）と、を有する電気化学的センサ装置（１）であって、作用電極（２０）が一つずつ設けられた複数の測定部（１５，１６）を含み、作用電極（２０）は、測定部（１５，１６）の底面から突出して形成された導電性の複数の突出部（５１）を有する電気化学的センサ装置（１）とする。
PCT/JP2008/063667 2007-09-07 2008-07-30 電気化学的センサ装置及びこれを用いた電気化学的測定方法 WO2009031375A1 (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
US12/733,533 US8303800B2 (en) 2007-09-07 2008-07-30 Electrochemical sensor device and electrochemical measuring method using the same
JP2009531162A JP5050251B2 (ja) 2007-09-07 2008-07-30 電気化学的センサ装置及びこれを用いた電気化学的測定方法

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007233358 2007-09-07
JP2007-233358 2007-09-07

Publications (1)

Publication Number Publication Date
WO2009031375A1 true WO2009031375A1 (ja) 2009-03-12

Family

ID=40428699

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2008/063667 WO2009031375A1 (ja) 2007-09-07 2008-07-30 電気化学的センサ装置及びこれを用いた電気化学的測定方法

Country Status (3)

Country Link
US (1) US8303800B2 (ja)
JP (1) JP5050251B2 (ja)
WO (1) WO2009031375A1 (ja)

Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2011002385A (ja) * 2009-06-19 2011-01-06 Univ Of Tokyo 人工脂質二重膜を用いた電流計測装置
JP2011193758A (ja) * 2010-03-18 2011-10-06 National Institute Of Advanced Industrial Science & Technology 薬剤感受性試験用バイオチップ
WO2012033181A1 (ja) * 2010-09-10 2012-03-15 国立大学法人 筑波大学 培養方法及び培養装置
US20120247979A1 (en) * 2010-06-17 2012-10-04 Massachusetts Institute Of Technology Method for Enhancing Current Throughput in an Electrochemical System
US20120312689A1 (en) * 2011-06-10 2012-12-13 Canon Kabushiki Kaisha Pump
WO2018070113A1 (ja) * 2016-10-14 2018-04-19 ソニーセミコンダクタソリューションズ株式会社 電位検出基板および電位計測装置
JP2019184390A (ja) * 2018-04-09 2019-10-24 凸版印刷株式会社 電気化学センサ用電極チップ及びその製造方法
JP2020505605A (ja) * 2017-01-30 2020-02-20 インターナショナル・ビジネス・マシーンズ・コーポレーションＩｎｔｅｒｎａｔｉｏｎａｌ Ｂｕｓｉｎｅｓｓ Ｍａｃｈｉｎｅｓ Ｃｏｒｐｏｒａｔｉｏｎ 強化されたセンサ信号及び感度のためのナノパターン付きバイオセンサ電極
JPWO2021220956A1 (ja) * 2020-04-28 2021-11-04
WO2022118727A1 (ja) * 2020-12-01 2022-06-09 デンカ株式会社 検出装置
JPWO2023026820A1 (ja) * 2021-08-27 2023-03-02
JP2023054424A (ja) * 2021-10-04 2023-04-14 国立研究開発法人物質・材料研究機構 マルチウェルプレート、電気化学測定方法、測定装置、自動測定システム、及び、製造方法

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2953542A4 (en) * 2013-02-06 2016-10-05 California Inst Of Techn MINIATURIZED IMPLANTABLE ELECTROCHEMICAL SENSORS
EP2827141B1 (en) * 2013-07-19 2019-09-18 Stichting IMEC Nederland Device and method for electrochemical gas sensing
WO2015192010A1 (en) * 2014-06-13 2015-12-17 Wafergen, Inc. Systems for single or multiple cell counting and dispensing
WO2017007427A1 (en) * 2015-07-06 2017-01-12 Nanyang Technological University Chemical sensor for heavy metal detection
US10820844B2 (en) 2015-07-23 2020-11-03 California Institute Of Technology Canary on a chip: embedded sensors with bio-chemical interfaces
US10213144B2 (en) 2016-01-25 2019-02-26 International Business Machines Corporation Nanopatterned biosensor electrode for enhanced sensor signal and sensitivity
US10612078B2 (en) * 2017-02-13 2020-04-07 California Institute Of Technology Integrated electrochemical nucleic acid based sensors and related platforms
US10548530B2 (en) 2017-03-01 2020-02-04 International Business Machines Corporation Biosensor calibration structure containing different sensing surface area
US11134868B2 (en) * 2017-03-17 2021-10-05 Medtronic Minimed, Inc. Metal pillar device structures and methods for making and using them in electrochemical and/or electrocatalytic applications
EP3396355A1 (en) * 2017-04-27 2018-10-31 Pharmafluidics NV Lateral detection of fluid properties
US11523757B2 (en) * 2019-08-01 2022-12-13 Medtronic Minimed, Inc. Micro-pillar working electrodes design to reduce backflow of hydrogen peroxide in glucose sensor
EP3951374A1 (en) * 2020-08-03 2022-02-09 Consejo Superior de Investigaciones Científicas (CSIC) Biosensor system for multiplexed detection of biomarkers

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH01174960A (ja) * 1987-12-29 1989-07-11 Fujitsu Ltd 電極構造体
JP2002170557A (ja) * 2000-12-01 2002-06-14 Toyota Central Res & Dev Lab Inc 電 極
JP2004085392A (ja) * 2002-08-27 2004-03-18 Fujitsu Ltd 炭素元素線状構造体を用いた電界効果トランジスタ化学センサー
JP2006119051A (ja) * 2004-10-22 2006-05-11 Shimadzu Corp 微粒子充填型マイクロチップ

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5427663A (en) * 1993-06-08 1995-06-27 British Technology Group Usa Inc. Microlithographic array for macromolecule and cell fractionation
WO1998049549A1 (en) * 1997-04-30 1998-11-05 Orion Research, Inc. Capillary electrophoretic separation system
JP2000009679A (ja) 1998-06-29 2000-01-14 Matsushita Electric Ind Co Ltd グルコースセンサおよびグルコースの定量法
JP3515908B2 (ja) 1998-09-24 2004-04-05 エヌ・ティ・ティ・アドバンステクノロジ株式会社 微少量オンラインバイオセンサー及びその製造方法
US6974526B2 (en) * 2001-05-01 2005-12-13 Calibrant Biosystems, Inc. Plastic microfluidics enabling two-dimensional protein separations in proteome analysis
EP2233564A3 (en) * 2002-10-30 2012-11-21 Hitachi, Ltd. Cell culture sheet comprising a functional substrate with a group of columnar micro-pillars and its manufacturing method
JP2006201080A (ja) 2005-01-21 2006-08-03 Osaka Prefecture バイオセンサーチップ
JP2008539063A (ja) * 2005-04-26 2008-11-13 キム，チル−ヤング 殺菌水製造装置、殺菌水噴霧装置、及びこれに使用される塩カプセル
WO2007059194A1 (en) * 2005-11-15 2007-05-24 Massachusetts Institute Of Technology Iso-dielectric separation apparatus and methods of use

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH01174960A (ja) * 1987-12-29 1989-07-11 Fujitsu Ltd 電極構造体
JP2002170557A (ja) * 2000-12-01 2002-06-14 Toyota Central Res & Dev Lab Inc 電 極
JP2004085392A (ja) * 2002-08-27 2004-03-18 Fujitsu Ltd 炭素元素線状構造体を用いた電界効果トランジスタ化学センサー
JP2006119051A (ja) * 2004-10-22 2006-05-11 Shimadzu Corp 微粒子充填型マイクロチップ

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
WATARU SATO ET AL.: "Kaimen choryoku o riyo shita bisho soeki kiko", PAPERS OF TECHNICAL MEETING ON CHEMICAL SENSOR ENGINEERING,IEE,JAPAN,ISSUED BY THE INSTITUTE OF ELECTRICAL ENGINEERS OF JAPAN, 28 November 2003 (2003-11-28), pages 149 - 154 *

Cited By (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2011002385A (ja) * 2009-06-19 2011-01-06 Univ Of Tokyo 人工脂質二重膜を用いた電流計測装置
JP2011193758A (ja) * 2010-03-18 2011-10-06 National Institute Of Advanced Industrial Science & Technology 薬剤感受性試験用バイオチップ
US20120247979A1 (en) * 2010-06-17 2012-10-04 Massachusetts Institute Of Technology Method for Enhancing Current Throughput in an Electrochemical System
US8753492B2 (en) * 2010-06-17 2014-06-17 Massachusetts Institute Of Technology Method for enhancing current throughput in an electrochemical system
WO2012033181A1 (ja) * 2010-09-10 2012-03-15 国立大学法人 筑波大学 培養方法及び培養装置
JPWO2012033181A1 (ja) * 2010-09-10 2014-01-20 国立大学法人 筑波大学 培養方法及び培養装置
US9217142B2 (en) 2010-09-10 2015-12-22 University Of Tsukuba Culture method and culture device for culturing cells adhered onto an electrode layer
US20120312689A1 (en) * 2011-06-10 2012-12-13 Canon Kabushiki Kaisha Pump
US8920621B2 (en) * 2011-06-10 2014-12-30 Canon Kabushiki Kaisha Pump
WO2018070113A1 (ja) * 2016-10-14 2018-04-19 ソニーセミコンダクタソリューションズ株式会社 電位検出基板および電位計測装置
JP2020505605A (ja) * 2017-01-30 2020-02-20 インターナショナル・ビジネス・マシーンズ・コーポレーションＩｎｔｅｒｎａｔｉｏｎａｌ Ｂｕｓｉｎｅｓｓ Ｍａｃｈｉｎｅｓ Ｃｏｒｐｏｒａｔｉｏｎ 強化されたセンサ信号及び感度のためのナノパターン付きバイオセンサ電極
JP2019184390A (ja) * 2018-04-09 2019-10-24 凸版印刷株式会社 電気化学センサ用電極チップ及びその製造方法
JP7127339B2 (ja) 2018-04-09 2022-08-30 凸版印刷株式会社 電気化学センサ用電極チップ及びその製造方法
JPWO2021220956A1 (ja) * 2020-04-28 2021-11-04
WO2021220956A1 (ja) * 2020-04-28 2021-11-04 デンカ株式会社 検出装置及び検出方法
JP7569847B2 (ja) 2020-04-28 2024-10-18 デンカ株式会社 検出装置及び検出方法
WO2022118727A1 (ja) * 2020-12-01 2022-06-09 デンカ株式会社 検出装置
JPWO2022118727A1 (ja) * 2020-12-01 2022-06-09
JP7606536B2 (ja) 2020-12-01 2024-12-25 デンカ株式会社 検出装置
JPWO2023026820A1 (ja) * 2021-08-27 2023-03-02
WO2023026820A1 (ja) * 2021-08-27 2023-03-02 デンカ株式会社 溶液供給装置、検出セット及び検出方法
JP7675194B2 (ja) 2021-08-27 2025-05-12 デンカ株式会社 溶液供給装置、検出セット及び検出方法
JP2023054424A (ja) * 2021-10-04 2023-04-14 国立研究開発法人物質・材料研究機構 マルチウェルプレート、電気化学測定方法、測定装置、自動測定システム、及び、製造方法

Also Published As

Publication number Publication date
US20110042237A1 (en) 2011-02-24
US8303800B2 (en) 2012-11-06
JP5050251B2 (ja) 2012-10-17
JPWO2009031375A1 (ja) 2010-12-09

Similar Documents

Publication Publication Date Title
WO2009031375A1 (ja) 電気化学的センサ装置及びこれを用いた電気化学的測定方法
WO2008040998A3 (en) Systems and methods for determining a substantially hematocrit independent analyte concentration
MX2010004817A (es) Tiras de prueba y sistema para medir niveles de analito en una muestra de fluido.
WO2008108124A1 (ja) ホウ素ドープ導電性ダイヤモンド電極を用いた電気化学的分析方法
WO2014100027A3 (en) System and method for production reservoir and well management using continuous chemical measurement
TW200602634A (en) Microfluidic analytical system with position electrodes
NO20063898L (no) Elektrokjemisk biosensor
BRPI0510668A (pt) métodos, sistemas e dispositivos para testar sensores de gás e corrigir saìda de sensores de gás
EP1947452A4 (en) METHOD FOR SPECIFIC DETECTION OF TEST SUBSTANCE USING PHOTOCOURANT, AND ELECTRODE, MEASURING CELL AND MEASURING DEVICE FOR IDOINE USE
WO2011003035A3 (en) Analyte sensor
WO2008157403A3 (en) Method and apparatus for metal nanoparticle electrocatalytic amplification
WO2009034284A8 (en) Strip for an electrochemical meter
WO2010120364A3 (en) Impedimetric sensors using dielectric nanoparticles
EA200601769A1 (ru) Количественный анализ переходных процессов местной коррозии
EP1742045A4 (en) METHOD FOR MEASURING BLOOD COMPONENTS AND BIOSENSOR AND MEASURING INSTRUMENT FOR USE THEREIN
WO2008027098A3 (en) Biosensor for measurement of species in a body fluid
MX355854B (es) Sistema y metodo para detectar sensores utilizados y secados.
WO2009157755A3 (en) Soil sensor
WO2001075430A3 (en) Sensor for electrochemical measurement
HK1212184A1 (en) System and method for determining hematocrit insensitive glucose concentrations
WO2007094805A3 (en) Method for electrocatalytic protein detection
WO2010076556A3 (en) A conductivity measurement cell
DK1742063T3 (da) System til differentiel bestemmelse af mængden af et proteolytisk enzym i en legemsvæske
WO2010068653A3 (en) Combined optical and resistance measuring apparatus and method
SG159463A1 (en) Method for detecting biomolecules and use thereof

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 08791898

Country of ref document: EP

Kind code of ref document: A1

DPE1 Request for preliminary examination filed after expiration of 19th month from priority date (pct application filed from 20040101)
DPE1 Request for preliminary examination filed after expiration of 19th month from priority date (pct application filed from 20040101)
WWE Wipo information: entry into national phase

Ref document number: 2009531162

Country of ref document: JP

WWE Wipo information: entry into national phase

Ref document number: 12733533

Country of ref document: US

NENP Non-entry into the national phase

Ref country code: DE

122 Ep: pct application non-entry in european phase

Ref document number: 08791898

Country of ref document: EP

Kind code of ref document: A1